Comparision of matrix-assisted laser desorption ionization-time of flight (MALDI-TOF MS) with API ID 32C and VITEK 2 for the identification of Trichosporon species

Abstract

ÖZ Amaç Anahtar kelimeler: Trichosporon, identifikasyon, MALDİ TOF MS ABSTRACT Comparision of Matrix-Assisted Laser Desorption Ionizationtime of Flight (MALDI-TOF MS) with API ID 32C and VITEK 2 For the Identification of Trichosporon Species Objective: Trichosporon species have a widespread distribution in the nature and human skin and mucosa can be colonized with Trichosporon species. Invasive infections caused by Trichosporon species are uncommon but frequently fatal in immunosuppressive patients. Correct identification of Trichosporon species is challenging but important for appropriate treatment approches. As an alternative to phenotypic and genome-based identification techniques, Matrix-assisted laser desorption ionizationtime of flight (MALDI-TOF) mass spectrometry (MS) is emerging as a rapid and accurate identification method. In this study we aimed to evaluate MALDI-TOF MS (Bruker Daltonics, Bremen, Germany)