Comparing the Variability Between Measurements for Sarcopenia Using Magnetic Resonance Imaging and Computed Tomography Imaging

Tandon, Puneeta; Mourtzakis, Marina; Low, Gavin; Zenith, Laura; Ney, Michael; Carbonneau, Michelle; Alaboudy, Alshimaa; Mann, Sumeer A.; Esfandiari, Nina; Ma, Mang

doi:10.1111/ajt.13832

Cited by 44 publications

(41 citation statements)

References 3 publications

(1 reference statement)

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“…Although only 8 patients in this cohort had both CT and MRI scans available for comparative analysis, we could not identify any significant differences in measurement of cross‐sectional muscle area values between the 2 modalities, in keeping with an analysis of scans from 61 patients recently published by Tandon et al The strong agreement between these 2 modalities supports the use of either CT or MRI imaging in future studies investigating cross‐sectional muscle area and sarcopenia.…”

Section: Discussionsupporting

confidence: 84%

Relationship Between Total Body Protein and Cross‐Sectional Skeletal Muscle Area in Liver Cirrhosis Is Influenced by Overhydration

Wells¹,

McCall

Plank³

2019

Liver Transpl

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Section: Discussionsupporting

confidence: 84%

Relationship Between Total Body Protein and Cross‐Sectional Skeletal Muscle Area in Liver Cirrhosis Is Influenced by Overhydration

Wells¹,

McCall

Plank³

2019

Liver Transpl

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“…Preliminary data published by our site suggests that MRI and CT performed on the same patients are correlated for muscle mass quantification 35 . Larger studies and studies evaluating the detection of longitudinal changes comparing both modalities are needed to further support the interchangeability of these two scanning methods.…”

Section: Use Of the Subjective Global Assessment (Sga) In Cirrhosismentioning

confidence: 87%

A Model to Identify Sarcopenia in Patients With Cirrhosis

Tandon

Low

Mourtzakis

et al. 2016

Clinical Gastroenterology and Hepatology

178

180

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“…Imaging (CT/MRI) is often performed during LT assessment and routine follow‐up and, therefore, may be opportunistically applied to evaluate SMM in pediatric and adult liver populations without additional cost and radiation risk. MRI and CT are cited as the gold standard for body composition assessment, and they can be used interchangeably to quantify SMM . The major limitation of CT is the radiation exposure, particularly in pediatrics .…”

Section: Discussionmentioning

confidence: 99%

“…MRI and CT are cited as the gold standard for body composition assessment, and they can be used interchangeably to quantify SMM. (2,45) The major limitation of CT is the radiation exposure, particularly in pediatrics. (46) MRI does not involve radiation, but the high cost and the need for trained analysts may limit serial measurements.…”

Section: Discussionmentioning

confidence: 99%

Sarcopenia in Chronic Liver Disease: Impact on Outcomes

et al. 2019

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Malnutrition is a common complication in patients with end‐stage liver disease (ESLD) awaiting liver transplantation (LT). Malnutrition and sarcopenia overlap in etiology and outcomes, with sarcopenia being defined as reduced skeletal muscle mass and muscle function. The purpose of this review was to identify the prevalence of sarcopenia with and without obesity in adults and children with ESLD and to assess the methodological considerations in sarcopenia diagnosis and the association of sarcopenia with pre‐ and post‐LT outcomes. A total of 38 articles (35 adult and 3 pediatric articles) retrieved from PubMed or Web of Science databases were included. In adults, the prevalence rates of pre‐LT sarcopenia, pre‐LT sarcopenic obesity (SO), post‐LT sarcopenia, and post‐LT SO were 14%‐78%, 2%‐42%, 30%‐100%, and 88%, respectively. Only 2 adult studies assessed muscle function in patients diagnosed with sarcopenia. The presence of pre‐LT sarcopenia is associated with higher wait‐list mortality, greater postoperative mortality, higher infection risk and postoperative complications, longer intensive care unit (ICU) stay, and ventilator dependency. The emerging pediatric data suggest that sarcopenia is prevalent in pre‐ and post‐LT periods. In 1 pediatric study, sarcopenia was associated with poor growth, longer perioperative length of stay (total/ICU) and ventilator dependency, and increased rehospitalization in children after LT. In conclusion, there is a high prevalence of sarcopenia in adults and children with ESLD. Sarcopenia is associated with adverse clinical outcomes. The present review is limited by heterogeneity in the definition of sarcopenia and in the methodological approaches in assessing sarcopenia. Future studies are needed to standardize the sarcopenia diagnosis and muscle function assessment, particularly in the pediatric population, to enable early identification and treatment of sarcopenia in adults and children with ESLD.

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Comparing the Variability Between Measurements for Sarcopenia Using Magnetic Resonance Imaging and Computed Tomography Imaging

Cited by 44 publications

References 3 publications

Relationship Between Total Body Protein and Cross‐Sectional Skeletal Muscle Area in Liver Cirrhosis Is Influenced by Overhydration

Relationship Between Total Body Protein and Cross‐Sectional Skeletal Muscle Area in Liver Cirrhosis Is Influenced by Overhydration

A Model to Identify Sarcopenia in Patients With Cirrhosis

Sarcopenia in Chronic Liver Disease: Impact on Outcomes

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