Comparing the risk factors of coronary artery diseases in patients with stenotic and ectatic lesions

Abstract

INTRODUCTIONIn the start of 20th century, heart diseases are the causes of 10% all deaths in world which this rate increased to 50% in the start of 21th century in developed countries and 25% in developing countries. It was predicted that until year 2020 heart diseases will due to 25 million deaths in year. 1-2Half of the deaths caused by cardiovascular diseases directly caused by coronary artery lesion and 20% were due to stroke. Coronary artery disease in mostly cases caused by atherosclerosis process. Coronary artery aneurysm is an aneurysm (more than 1.5 times the diameter of the arteries), which is also called coronary artery ectatic as the majority of aneurysms have atherosclerotic resource. 4 ABSTRACT Background: Coronary artery ectatic usually have relation with hyperlipidemia, systemic hypertension and male gender and its diagnosis done by angiography. Due to lack of proved risk factors for incidence of coronary artery ectatic lesions and also its important. The aim of this study was to compare the risk factors of coronary artery in patients with ectatic and stenotic lesions. Methods: This is a descriptive and analytical study that has been done on 300 patients hospitalized in Ardabil city hospital. Patients were enrolled according to the criteria and undergone to angiography. According to result of angiography, patients who have ectatic lesions as the first group and patients whose lesions were stenotic were named as the second group. Information obtained from patients entered in the checklist and analyzed by statistical methods in SPSS.16. Results: 22% of patients with ectatic lesions and 78% with stenotic lesions in patients with ectatic lesions. The mean age was 58.7 years and 74.2% were male and in patients with lesions stenotic the mean age was 60.7 years and 54.3% were male. Based on angiography results, in patients with ectatic lesions 42.4% have engaged in a carotid and 44.4% were two clashes coronary arteries in group stenotic. 34.7% of patients have history of previous mi, 32.9% history of coronary artery disease, 54.7% history of smoking, 56% had diabetes mellitus and 56% had hypertension. History of previous MI (p=0.028), smoking (p=0.04) and diabetes mellitus (p=0.001) and history of coronary artery disease are effective risk factors in two groups. Conclusions:The results showed that previous history of myocardial infarction, smoking and DM have significant relation with type of lesions.