Comparing the responses of grain fed feedlot cattle under moderate heat load and during subsequent recovery with those of feed restricted thermoneutral counterparts: metabolic hormones

Wijffels, Gene; Sullivan, Mitchell J.; Stockwell, Sally; Briscoe, S; Anderson, Stephen; Li, Y; Costa, Cíntia Carol de Melo; McCulloch, Russell; Olm, J. C. W.; Cawdell-Smith, Judy; Gaughan, J. B.

doi:10.1007/s00484-023-02464-w

Cited by 2 publications

(4 citation statements)

References 85 publications

(122 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the same animals described in this study, strong negative linear relationships for thyroid stimulating hormone, T4, and adiponectin with rumen temperature were found (Wijffels et al 2023 ). The FRTN group uniquely showed positive linear relationships between rumen temperature and leptin, and DMI and leptin.…”

Section: Resultssupporting

confidence: 66%

“…In healthy animals attempting to reduce endogenous heat production, down regulation of the inflammatory response at the systemic level seems appropriate. The previous reports on the endocrine and metabolic response of these thermally challenged steers showed homeorhetic adjustments to the increased heat load and subsequent adjustment after the thermal challenge to arrive at similar metabolic hormone milieu and metabolic state as their FRTN counterparts (Wijffels et al 2023 ). Moreover, both the FRTN and TC steers had recovered and strongly increased DMI in PENS and Later PENS, and experienced rapid live weight gain; the treatment groups could not be differentiated on these performance measures.…”

Section: Concluding Commentsmentioning

confidence: 78%

“…This comparison is critical to discern the consequences of heat stress from those seen due to a sudden reduction in feed intake and subsequent realimentation (refeeding) in recovery. Descriptions of the performance and physiological responses, as well as the metabolic and metabolic hormone responses, have been reported elsewhere (Sullivan et al 2022 ; Wijffels et al 2022 ; 2023 ). The thermally challenged (TC) group was subjected to conditions typical of a moderate heatwave experienced over summer by feedlot cattle in southern Queensland, Australia.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Comparing the responses of grain-fed feedlot cattle under moderate heat load and during subsequent recovery with those of feed-restricted thermoneutral counterparts: blood cells and inflammatory markers

Wijffels,

Sullivan,

Stockwell

et al. 2023

Int J Biometeorol

Self Cite

View full text Add to dashboard Cite

Given the climate projections for livestock rearing regions globally, understanding the inflammatory status of livestock under various heat loads will be informative to animal welfare and management. A survey of plasma inflammatory markers was conducted, and blood leucocyte counts followed to investigate the capacity of the ~ 500 kg grain fed Black Angus steer to respond to and recover from a moderate heat load challenge. Two sequential cohorts of 12 steers were housed in climate-controlled rooms (CCR) for 18 days. A thermally challenged (TC) group (n = 2 × 6) experienced five consecutive periods: PreChallenge, Challenge, and Recovery within the CCR, and 40 days in outdoor pens (PENS and Late PENS). PreChallenge (5 days) and Recovery (7 days) delivered thermoneutral conditions, whereas in Challenge the TC steers experienced a diurnal temperature range of 28–35 °C. A feed-restricted thermoneutral (FRTN) treatment (n = 2 × 6) was run concurrently to differentiate between responses to reduced feed intake alone and moderate heat stress. Blood neutrophil counts were particularly sensitive to moderate heat load with higher numbers during Challlenge and in PENs. The plasma concentrations of TNFα and IL-1β were depressed in the TC group compared to the FRTN counterparts and remained so for 40 days after Challenge. Linear relationships of the concentrations of IL-1β, IL-10, and haptoglobin with rumen temperature or dry matter intake detected in the FRTN group were altered or absent in the TC group. The findings suggest significant impacts of moderate heat load on the inflammatory status of feedlot cattle.

show abstract

Section: Resultssupporting

confidence: 66%

Section: Concluding Commentsmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Comparing the responses of grain-fed feedlot cattle under moderate heat load and during subsequent recovery with those of feed-restricted thermoneutral counterparts: blood cells and inflammatory markers

Wijffels,

Sullivan,

Stockwell

et al. 2023

Int J Biometeorol

Self Cite

View full text Add to dashboard Cite

show abstract

“…Enzyme-linked immunosorbent assays were performed to measure the following inflammatory cytokines using kits as per the manufacturer’s instructions (R&D Systems, Minneapolis, MI, USA): interleukin 1β (Cat DY681), interleukin 6 (Cat DY686), interleukin 10 (Cat DY693B), and tumour necrosis factor-α (Cat DY690B) (In Vitro Technologies, Noble Park, VIC, Australia). Metabolic hormones, adiponectin and leptin, were measured as described in [ 18 ].…”

Section: Methodsmentioning

confidence: 99%

Using Recombinant Superoxide Dismutase to Control Oxidative Stress in the Gastrointestinal Tract of Cyclic Heat-Stressed Pigs

Le,

Zhao,

Furness

et al. 2023

Animals

View full text Add to dashboard Cite

Climate change is associated with an increased frequency and intensity of heat waves, posing a threat of heat stress to pig production. Heat stress compromises the efficiency of pig production partly due to causing oxidative stress, intestinal dysfunction, and inflammatory responses. Superoxide dismutase is an antioxidant enzyme reported to reduce oxidative stress and inflammation. Therefore, this experiment aimed to investigate whether recombinant superoxide dismutase (rSOD) could ameliorate oxidative stress and inflammatory responses in heat-stressed grower pigs. Sixty-four female pigs (Large White × Landrace, 27.8 ± 1.65 kg, mean ± SD) were randomly allocated to a control diet (standard grower feed, CON) or the control diet supplemented with 50 IU recombinant superoxide dismutase (rSOD) for 14 days. After acclimation to the diet, pigs were then housed under thermoneutral (TN, 20 °C, 35–50% relative humidity) or cyclic heat stress conditions (CHS, at 35 °C: 9 a.m. to 5 p.m. and 28 °C: 5 p.m. to 9 a.m., 35–50% relative humidity) for 3 days. Heat stress increased respiration rate (RR), skin and rectal temperature (RR and RT) (p < 0.001 for all), and reduced plasma thyroid hormone concentration (p < 0.001). The amount of oxidized glutathione (GSH:GSSG) was increased in the jejunum and ileum of CHS pigs. In the jejunum, rSOD also increased the amount of oxidized glutathione in both TN and CHS pigs, without any change in endogenous SOD activity. In the ileum, rSOD prevented increases in oxidized glutathione formation in the CHS pigs only. Taken together, this may reflect increased oxidative stress in both the jejunum and ileum in CHS pigs. Alternatively, rSOD increased the conversion of reduced to oxidized glutathione independently of CHS, possibly reflecting an increased overall SOD activity due to the addition of exogenous SOD. In conclusion, the use of in-feed SOD enzymes at a dose of 50 IU/kg may be a useful strategy for preventing oxidative stress in pigs.

show abstract

Comparing the responses of grain fed feedlot cattle under moderate heat load and during subsequent recovery with those of feed restricted thermoneutral counterparts: metabolic hormones

Cited by 2 publications

References 85 publications

Comparing the responses of grain-fed feedlot cattle under moderate heat load and during subsequent recovery with those of feed-restricted thermoneutral counterparts: blood cells and inflammatory markers

Comparing the responses of grain-fed feedlot cattle under moderate heat load and during subsequent recovery with those of feed-restricted thermoneutral counterparts: blood cells and inflammatory markers

Using Recombinant Superoxide Dismutase to Control Oxidative Stress in the Gastrointestinal Tract of Cyclic Heat-Stressed Pigs

Contact Info

Product

Resources

About