Comparing the epidemiology of hospital-acquired methicillin-resistant <i>Staphylococcus aureus</i> clone groups in Alberta, Canada

Bruzzese, S.; Bush, Kathryn; Leal, Jenine; Kim, J.; Vickers, David; Rusk, A.; Fathima, Sumana; Li, V.; Chui, Linda; Louie, Marie; Henderson, Elizabeth

doi:10.1017/s0950268816000376

Cited by 4 publications

(2 citation statements)

References 20 publications

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“…The adoption of a SWPB in our hospital is mostly adapted from best adult practices and includes the use of chlorhexidine (CHG) baths for skin antisepsis both pre and operatively (12). In addition, SWPB adopted use of nasal mupirocin ointment to de-colonize nasal carriers of Methicillin resistant Staphylococcus Aureus (MRSA) during the preoperative period, as this can be associated with a 2- to 14-fold increased risk of SSI (14–16). …”

Section: Methodsmentioning

confidence: 99%

Reducing Pediatric Sternal Wound Infections: A Quality Improvement Project

Delgado-Corcoran

Dorn

Pribble

et al. 2017

Pediatric Critical Care Medicine

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Objectives To evaluate whether a quality improvement intervention reduces sternal wound infection (SWI) rates in children after cardiac surgery. Design This is a pre- and post-intervention quality improvement study. Setting A 16-bed cardiac intensive care unit in a university-affiliated pediatric tertiary care children’s hospital. Patients All patients undergoing cardiac surgery via median sternotomy from January 2010 to December 2014 are included. The SWI rates for primary closure (PC) and delayed sternal closure (DSC) are reported per 100 sternotomies. The hospital acquired infection (HAI) records were used to identify pre- intervention cases, while post-intervention cases were collected prospectively. Intervention Implementation of a sternal wound prevention bundle (SWPB) during the preoperative, intraoperative and postoperative periods for cardiac surgical cases. Measurements and Main Results During the pre-intervention period, 32 (3.8%) patients developed SWI while only 19 (2.1%) developed SWI during the post-intervention period (p=0.04). The rates of SWI following PC were not significantly different pre- and post-intervention (2.4% vs. 1.6%; p=0.35). However, patients with DSC had significantly lower post-intervention infection rates (10.6% vs. 3.9%; p=0.02). Conclusions Implementation of a SWPB during the perioperative period was associated with lower SWI rates in surgeries with DSC.

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Section: Methodsmentioning

confidence: 99%

Reducing Pediatric Sternal Wound Infections: A Quality Improvement Project

Delgado-Corcoran

Dorn

Pribble

et al. 2017

Pediatric Critical Care Medicine

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“…3,4 Another challenge associated with Staphylococci is the development of multidrug resistant strains to various available antibiotics. 5 So we undertake the present study to estimate the prevalence of asymptomatic nasal carriage of Staphylococci among HCWs and impact of conventional decolonisation methods in a tertiary care hospital in West Bengal.…”

mentioning

confidence: 99%

Nasal Carriage of Staphylococci among Health Care Workers and Impact of Conventional Decolonisation Methods

Das¹,

Ghosh²,

Dhar³

2021

BJOHNS

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Introduction Staphylococci are one of the most common causes of nosocomial infections. The principal route of transmission of Staphylococci is the contaminated hands of health care workers (HCWs). Staphylococci can also be found as part of the nasal microbiota without causing overt disease. So we undertake the present study to estimate the prevalence of asymptomatic nasal carriage of Staphylococci among HCWs and impact of conventional decolonisation methods in a tertiary care hospital in West Bengal. Materials and Methods Nasal swabs were collected from anterior nares of HCWs for culture and antibiotic sensitivity test on day one. HCWs who were found to be carriers of Staphylococci were advised to apply mupirocin ointment to anterior nares twice daily along with chlorhexidinegluconate bath once daily for five days. All HCWs were also advised to practice standard hygiene protocol. All of them were re-tested for nasal swab culture and antibiotic sensitivity on day seven and day twenty eight. Results Nasal carriage of Staphylococci in the first, second and third culture report was found to be 64.28%, 7.14% and 24.49% respectively. Cefotaxime, cotrimoxazole and erythromycin were least effective against Staphylococci. There was variable sensitivity to clindamycin, gentamycin and ciprofloxacin. All strains of Staphylococci were highly sensitive to linezolid. All strains of Staphylococci except MRSA were highly sensitive to vancomycin. Conclusion The present study re-establishes the fact that HCWs carry Staphylococci in their nose in significantly high proportion. So different measures should be undertaken to minimise Staphylococci related nosocomial infections.

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