Abstract:Spatio-temporal spike patterns were suggested as indications of active cell assemblies. We developed the SPADE method to detect significant spatio-temporal patterns (STPs) with ms accuracy. STPs are defined as identically repeating spike patterns across neurons with temporal delays between the spikes. The significance of STPs is derived by comparison to the null-hypothesis of independence implemented by surrogate data. SPADE binarizes the spike trains and examines the data for STPs by counting repeated pattern… Show more
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