Comparing Mortality of Vaginal Sarcoma, Squamous Cell Carcinoma, and Adenocarcinoma in the Surveillance, Epidemiology, and End Results Database

Abstract

III.

WITHDRAWN: Primary vaginal sarcoma in a single center

“…Compared to women with squamous cell carcinoma and adenocarcinoma, patients diagnosed to have vaginal sarcomas tend to be younger, have larger tumors with less regional extension and lymph node positivity, and be treated primarily with surgery without radiation ( Ghezelayagh et al, 2015 ).…”

“…Primary vaginal sarcomas are aggressive neoplasms with different presenting characteristics and increased adjusted risk of mortality as compared to squamous cell and adenocarcinoma subtypes ( Ghezelayagh et al, 2015 ). Because of their low incidence and the lack of prospective studies, it is very difficult to reach conclusions regarding the best disease management recommendations for primary vaginal sarcoma.…”

Primary vaginal sarcoma in a single center

“…Although there are limited data specifically examining chemotherapy or radiation in vaginal sarcoma, the retrospective and prospective experience in gynecologic sarcomas echo the soft tissue sarcoma data. These data are primarily obtained for uterine sarcoma and suggest that postoperative therapy leads to a reduction in local relapse with no benefit in progression-free or overall survival ( Ghezelayagh et al, 2015 ). Because the poor prognosis of vaginal sarcoma, adjuvant chemotherapy is suitable for these patients, especially for those with poor prognostic factors.…”

Prognostic nomogram and treatment efficacy analysis for vaginal cancer: A SEER database and external validation study

“…Age and human papillomavirus infection are risk factors for its onset 3,5 . Accounting for about 80%–90% of vaginal cancer, squamous cell carcinoma is the most common type of pathology, 2,4 followed by adenocarcinoma, intraepithelial neoplasia, melanoma, sarcoma, and some other rare pathologic types 4,6,7 . Vaginal cancer most commonly metastasizes to the lung, followed by liver, bone, and brain 4,8 …”