Comparing cardiac CT angiography and MR angiography in evaluating left ventricular function and volumes

Abstract

Background: cardiovascular diseases are among the principal causes of mortality and morbidity worldwide. Prevention, early diagnosis and treatment can play an important role in reducing complication of cardiovascular diseases. Objectives: Considering increasing popularity of cardiac computed tomography CT angiography (CTA) in one side and also magnetic esonance angiography (MRA) as gold standard modality on the other side, we decided to perform this meta-analysis study to compare cardiac CTA and MRA in evaluating left ventricular volumes. Method: this study is a systematic review in which we included all studies with inclusion criteria and without exclusion criteria up to 30 December, 2019. Studies were selected after searching on different databases and articles in bibliography of included studies. Obtained studies were screened for quality. Required data were extracted and were then analyzed via STATA 11 statistical package. Results: among 90 articles obtained in primary search, finally 19 studies entered data extraction and synthesis. Based on our meta-analysis, standardized mean difference was -0.09 (95% CI -0.2, 0.02) for end systolic volume (ESV), -0.10 (95% CI -0.22, 0.01) for end diastolic volume (EDV), 0.10 (95% CI -0.01, 0.22) for ejection fraction (EF) and -0.09 (95% CI -0.23, 0.04) for stroke volume (SV). Conclusion: Results of this systematic review and meta-analysis showed that there is no statistically significant difference between CTA and MRA in evaluating ESV, EDV, EF and SV. Based on our findings, it can be interpreted that CTA has similar accuracy with MRA in evaluating ventricular volumes.