Comparative values of gated blood-pool SPECT and CMR for ejection fraction and volume estimation

Sibille, L.; Bouallègue, Fayçal Ben; Bourdon, A.; Micheau, Antoine; Vernhet-Kovacsik, Hélène; Mariano‐Goulart, Denis

doi:10.1097/mnm.0b013e32834155f1

Cited by 30 publications

(28 citation statements)

References 40 publications

(57 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As for RV EF, studies showed a significant correlation between GBPS and first-pass radionuclide ventriculography (15). Furthermore, as recently reported, GBPS has correlated well with CMR for the estimation of LV and RV parameters (16)(17)(18)(19).…”

supporting

confidence: 63%

“…In this respect, GBPS has the potential advantage of deriving RV volumes by countbased approaches rather than by geometric considerations. In a recent investigation, Sibille et al (18) reported that RV parameters assessed by GBPS correlated well with those obtained by CMR (r 5 0.80 for RV EDV, 0.86 for RV ESV, and 0.74 for RV EF). And Nichols et al (19) demonstrated greater correlation coefficients between these 2 methods in patients with primary pulmonary hypertension or tetralogy of Fallot (r 5 0.94 for RV EDV, 0.93 for RV ESV, and 0.85 for RV EF).…”

Section: Discussionmentioning

confidence: 82%

“…Prior studies have demonstrated correlation between GBPS and CMR for the assessment of LV indices (17,18,25,26). Although these studies enrolled heterogeneous patients with normal and abnormal left ventricles, it remained unclear whether GBPS correlated with CMR in a restricted DCM population with enlarged left ventricles.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluation of Left and Right Ventricular Ejection Fraction and Volumes from Gated Blood-Pool SPECT in Patients with Dilated Cardiomyopathy: Comparison with Cardiac MRI

et al. 2012

View full text Add to dashboard Cite

This prospective study evaluated the accuracy of electrocardiogram-gated blood-pool SPECT (GBPS) for the assessment of left ventricular (LV) and right ventricular (RV) ejection fraction (EF), end-diastolic volume (EDV), and end-systolic volume (ESV) in patients with dilated cardiomyopathy (DCM), using cardiac magnetic resonance (CMR) imaging as the reference standard. Methods: Thirty-two patients (24 men and 8 women; mean age, 51 y) with a diagnosis of idiopathic DCM underwent GBPS and CMR. LV and RV parameters including EDV, ESV, and EF from GBPS were calculated using fully automated gradient software and compared with those obtained by CMR. Results: Biventricular volumes were underestimated by GBPS, compared with CMR (P , 0.001). We found no statistical difference between these 2 methods in the assessment of LV EF (P 5 0.23), whereas RV EF was overestimated by GBPS (P , 0.001 vs. CMR). Regression analysis yielded significant correlations between GBPS and CMR in the assessments of biventricular parameters (r 5 0.83 for LV EDV, 0.88 for LV ESV, 0.89 for LV EF, 0.86 for RV EDV, 0.86 for RV ESV, and 0.62 for RV EF; all P , 0.001). Comparison of the deviations of RV indices between GBPS and CMR with the ratio of RV EDV to LV EDV showed that there was a statistically significant trend for RV volumes to be underestimated and for RV EF to be overestimated as the biventricular volumetric ratio decreased (r 5 0.61 for RV EDV, 0.68 for RV ESV, and 20.55 for RV EF; all P , 0.001). Conclusion: For patients with DCM, GBPS correlated well with CMR for the assessment of biventricular parameters, but RV indices should be cautiously interpreted.

show abstract

supporting

confidence: 63%

Section: Discussionmentioning

confidence: 82%

See 1 more Smart Citation

Evaluation of Left and Right Ventricular Ejection Fraction and Volumes from Gated Blood-Pool SPECT in Patients with Dilated Cardiomyopathy: Comparison with Cardiac MRI

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Nuclear imaging exists as one alternative to these other modalities. However, studies regarding the utility of nuclear imaging to assess RV EF, while showing good inter-study precision and comparability between different nuclear imaging modalities, has only been studied on small numbers of patients and to our knowledge there is only one study comparing nuclear imaging with MRI in a small number of patients [13][14][15]. Currently, MRI is considered the ''gold standard'' for assessing RV function [37,38].…”

Section: Discussionmentioning

confidence: 99%

“…The most commonly accepted method for assessment of RV EF is considered to be cardiac MRI, which is both costly and not readily available at all medical centers [9][10][11][12]. Nuclear imaging is also considered a reliable technique for measuring RV EF, though only one small study of 30 patients exists comparing it with cardiac MRI [13][14][15]. Other methods, such as bi-plane echocardiography and newer 3-dimensional methods, are still being evaluated [16][17][18][19].…”

mentioning

confidence: 99%

Utility of transthoracic echocardiography to estimate severity of right ventricular dysfunction: an MRI comparison study

Kapa

Eliáš

Connolly

et al. 2011

Int J Cardiovasc Imaging

View full text Add to dashboard Cite

Prognostic implications of severe right ventricular (RV) dysfunction are difficult to assess because of limitations in functional characterization using standard echocardiography (TTE) and the cost and availability of options such as MRI. We sought to determine how assessments of RV dysfunction via TTE correlate with RV ejection fraction (EF) by MRI. Patients undergoing MRI and TTE within 21 days of one another were included. Left ventricular (LV) and RV EF were recorded from MRI and subjective assessment of RV function (normal, mild, moderate, or severe dysfunction), right ventricular index of myocardial performance (RIMP), and right ventricular systolic pressure (RVSP) were recorded from TTE. Patients were considered to have significant RV dysfunction if EF ≤ 35% on MRI and normal function if EF ≥ 45%. A total of 474 patients were included (age 50 ± 12, 57% male). Of these, 363 (76.6%) had normal function, 54 (11.4%) had mild dysfunction, 41 (8.6%) had moderate dysfunction, and 16 (3.4%) had severe dysfunction on TTE. Moderate or severe dysfunction had good sensitivity (80%) and specificity (97%) for RV EF ≤ 35%. Furthermore, RIMP > 0.70 and RVSP > 70 mm Hg were very specific for RV EF ≤ 35% (sensitivity = 29%, 22%, respectively; specificity = 98%, 99%, respectively). Specificity and sensitivity of TTE assessments did not change if LV function or disease indication was considered. A subjective assessment of moderate to severe RV dysfunction on TTE compares favorably with quantitative MRI assessment of the RV EF. Further study is needed to evaluate whether this comparability is true across institutions.

show abstract

Imaging the Heart in the Cancer Patient

Fox

Strausś

2012

Nuclear Oncology

View full text Add to dashboard Cite

Comparative values of gated blood-pool SPECT and CMR for ejection fraction and volume estimation

Abstract: GBPS is a simple and widely available technique that can assess both LVEF and RVEF, and volumes with slight differences compared with CMR.

Cited by 30 publications

References 40 publications

Evaluation of Left and Right Ventricular Ejection Fraction and Volumes from Gated Blood-Pool SPECT in Patients with Dilated Cardiomyopathy: Comparison with Cardiac MRI

Evaluation of Left and Right Ventricular Ejection Fraction and Volumes from Gated Blood-Pool SPECT in Patients with Dilated Cardiomyopathy: Comparison with Cardiac MRI

Utility of transthoracic echocardiography to estimate severity of right ventricular dysfunction: an MRI comparison study

Imaging the Heart in the Cancer Patient

Contact Info

Product

Resources

About