Comparative tissue expression of American lobster (Homarus americanus) immune genes during bacterial and scuticociliate challenge

Clark, Kevin; Acorn, Adam R.; Wang, Haili; Greenwood, Spencer J.

doi:10.1016/j.fsi.2015.10.035

Cited by 7 publications

(2 citation statements)

References 42 publications

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“…Las proteínas de fase aguda APPs son proteínas de hemolinfa solubles sintetizadas en el hepatopáncreas en H. americanus (Clark et al, 2013). Se liberan en el torrente sanguíneo durante la infección, los traumas, los procesos inflamatorios y el estrés, sugiriéndose su empleo como marcadores de la activación inmune innata en crustáceos (Clark et al, 2015). Se conoce muy poco sobre las APPs de crustáceos pero ha sido identificada la proteína A amiloide sérica de fase aguda (SAA) en ensayos con la especie H. americanus en desafíos por patógenos (Clark et al, 2013).…”

Section: Vías Documentadasunclassified

Manano oligosacaridos como prebioticos en acuicultura de crustaceos

Gainza¹,

Romero²

2017

lajar

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RESUMEN.Los prebióticos tienen el potencial de incrementar la eficiencia y sostenibilidad de la producción acuícola. Uno de los prebióticos más promisorios en acuicultura son los Manano oligosacáridos (MOS). Estos MOS son moléculas de carbohidratos complejos derivados de la pared de la célula de la levadura Saccharomyces cerevisiae, que impiden la adhesión de patógenos bacterianos porque actúan bloqueando la adherencia de las lectinas microbianas con los carbohidratos presentes en la superficie de las células intestinales. Esta prevención de la adhesión impide la colonización y proceso infectivo de los patógenos. La ventaja del uso de MOS es que puede prevenir infecciones a través de mecanismos diferentes a los utilizados por los antibióticos. Este artículo muestra los avances obtenidos en uso de MOS como prebióticos en la acuicultura, en particular en el cultivo de crustáceos, donde han generado respuestas positivas en todas las experiencias actuando sobre el incremento del crecimiento, la supervivencia, modulando la respuesta inmune y modificando la morfología del tracto digestivo. La identificación de las cepas que son promovidas o excluidas y la caracterización de la acción moduladora en la microbiota resultante quedan abiertas como uno de los campos a desarrollar en conjunto con la extensión de estos resultados a la práctica productiva. Palabras clave: crustáceos, manano oligosacáridos, MOS, prebióticos, microbiota, crecimiento. Mannan oligosaccharides as prebiotics in crustacean aquacultureABSTRACT. Probiotics have the potential to increase the efficiency and sustainability of aquaculture production. The mannan-oligosaccharides (MOS) are complex carbohydrates derived from the cell wall of the yeast Saccharomyces cerevisiae, which act by blocking adherence of bacterial lectins to carbohydrates on the surface of intestinal cells; this action prevents colonization and infection processes carried out by bacterial pathogens. In this work, we review the current evidence about the use of MOS as prebiotics in shellfish aquaculture, enlightening the positive responses in most of the experiences, such as improvement in growth and survival, modulating the immune response and modifying the morphology of the digestive tract. The identification of strains that are promoted or excluded, and the characterization of the resulting modulating action in gut´s microbiota, remains open as one of the fields to be developed in conjunction with the extension of these results to the productive practice.

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Section: Vías Documentadasunclassified

Manano oligosacaridos como prebioticos en acuicultura de crustaceos

Gainza¹,

Romero²

2017

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“…The majority of RNA-Seq transcriptomic studies on American lobsters have focused on crustacean immune and nervous system function in an evolutionary context with limited consideration of how local ocean conditions influence these processes (Clark et al 2013a;Clark et al 2013b;Clark et al 2013c;Clark et al 2015;McGrath et al 2016). In the past year, however, two published studies Addressing shellfish disease and preventing reduced larval settlement in a warming GoM Amidst the warming in the GoM, new lobster management goals begin to emerge.…”

Section: American Lobster Transcriptomicsmentioning

confidence: 99%

Shifting Transcriptomes In Changing Waters

Lopez-Anido¹

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My sincerest thank you to, My thesis advisor Dr. Helen Poulos for guiding and reassuring me throughout every step of this project. Her meaningful mentorship and heartfelt advice supported the success of both this thesis and my time at Wesleyan. My mentors Dr. Heather Hamlin and Dr. Amalia Harrington without whom this thesis would not have been possible. I am most thankful for the time I have spent working with and learning from Heather and Amalia. Their never-ending kindness, encouragement, patience, and creativity allowed me to pursue this project and grow as a young scientist.My research and academic advisor Dr. Barry Chernoff for his wisdom and enthusiasm. Through rigorous edits and continuous curiosity, Barry helped me craft the second chapter of this thesis. Thank you for always encouraging me to challenge myself and think in new ways.Alexis Sher, my thesis mentor for all of her edits on very rough drafts. Alexis gifted me positivity throughout the writing process, even during the most frustrating bits.All my friends, especially Julia Cella, Benjy Cahill, Sophie Scobell, and Emma Trapani, for being there during all of my thesis freak outs and for reminding me to breathe. I would not have survived this past year without the love I have received from them. I feel forever grateful for the amount of joy and inspiration my friends have brought me. Thank you for staying by my side throughout it all.Mi familia, mami, papi, Camila, y Virginia por todo su apoyo y amor. Gracias por enseñarme cómo pensar con creatividad y vivir con amor. ¡Los quiero muchísmo! 4 Table of Contents INTRODUCTION .

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