Comparative Study to Evaluate the Effects of Intranasal Dexmedetomidine Versus Midazolam as a Premedication Agent in Children Undergoing Elective Surgery

Abstract

BACKGROUNDIntranasal route of drug administration is a practical option as a non-invasive alternative to intravenous route especially for children. We conducted a study to compare the effects of Dexmedetomidine and Midazolam administered as premedication agents through intranasal route. The primary outcome measures were assessing the sedation status upon parental separation and behaviour level during induction. The secondary outcome measures were assessing the acceptance of intravenous cannulation and acceptance of facemask during induction.