2015
DOI: 10.14260/jemds/2015/2167
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Comparative Study to Assess the Efficacy Between Intramuscular and Vaginal Micronized Progesterone to Prevent Threatened Premature Labour

Abstract: Preterm birth remains a major clinical problem. Prematurity is not only a major cause of perinatal mortality but also leads to greater risk for short and long term complications including disability and impediments in growth and mental development. To compare vaginal with intramuscular progesterone administration to prevent preterm labor and to detect the effect of both on the uterine and foetal circulations. STUDY DESIGN: comparative interventional study. POPULATION: 100 pregnant women attending NRSMCH Kolkat… Show more

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Cited by 1 publication
(3 citation statements)
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References 31 publications
(49 reference statements)
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“…It was observed in the present study that 21(40%) patients had preterm delivery and the mean gestational age at delivery was 35.5±2.5 weeks in the progesterone group. This finding was consistent with the studies of Patra K et al [14] , Wajid R et al [15] and Abdou AM [16] .…”
Section: Discussionsupporting
confidence: 93%
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“…It was observed in the present study that 21(40%) patients had preterm delivery and the mean gestational age at delivery was 35.5±2.5 weeks in the progesterone group. This finding was consistent with the studies of Patra K et al [14] , Wajid R et al [15] and Abdou AM [16] .…”
Section: Discussionsupporting
confidence: 93%
“…It was observed in the present study that 7(13%) patients had vaginal dryness, 13(25%) patients had constipation, 4(8%) patients had dizziness. This is concordant to the studies of Erny R et al [19] , Patra K et al [14] , Ashoush S et al [12] , Maher MA et al [20] and El-Gharib MN et al [21] . Progesterones may entail many side effects such as mood swings, dyspepsia, headache, constipation, dyspareunia, drowsiness, fatigue, genital itching.…”
Section: Discussionsupporting
confidence: 90%
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