Comparative study on the monosaccharide compositions, antioxidant and hypoglycemic activities in vitro of intracellular and extracellular polysaccharides of liquid fermented Coprinus comatus

Cao, Hui; Ma, Shan; Guo, Hong; Cui, Xiaowei; Wang, Shanshan; Zhong, Xiaofei; Wu, Yumeng; Zheng, Wenxiu; Wang, Haonan; Yu, Jing; Ma, Lai; Han, Chunchao

doi:10.1016/j.ijbiomac.2019.08.017

Cited by 55 publications

(25 citation statements)

References 15 publications

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“…There are some findings in the literature regarding the antioxidant activities of C. comatus obtained through the test methods used in the current study (Asatiani et al, 2007a,b;Liv et al, 2010;Akata et al, 2012;Kalaw & Albinto, 2014;Sadi et al, 2015;Seklic et al, 2016;Tesanovic et al, 2017;Cao et al, 2019). According to the data in these studies, the mushroom species in question showed 72.06% activity at a concentration of 2.0 mg/ml in -carotene assay (Asatiani et al, 2007a, b).…”

Section: Chemical Compositions Of Mushroom Extractsmentioning

confidence: 51%

Chemical compositions and antioxidant activities of four different mushroom species collected from Turkey

Tepe

2021

International Journal of Secondary Metabolite

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Many researchers agree that edible mushrooms have beneficial effects on human health. The aim of this study is to investigate the chemical composition and antioxidant activities of methanol extracts obtained from Coprinus comatus, Hydnum repandum, Agaricus impudicus ve Sarcodon imbricatus collected from Yuvacık-İzmit, Kastamonu, and Uzungöl-Trabzon. Spectrophotometric analysis showed that the total phenolic (64.69 mg GAEs/g) and flavonoid (1.73 mg QEs/g) content of S. imbricatus was higher than that of the others. In line with its superiority in phytochemical composition analyzes, S. imbricatus extract showed the highest activity in -carotene bleaching, DPPH free radical scavenging and reducing power assays (836.0, 89.0 and 267.0 mg TEs/g extract, respectively). Metal chelating test resulted in the superiority of A. impudicus (1282.0 mg TEs/g). Relative antioxidant capacity index (RACI) value of S. imbricatus was quite high compared to other extracts (0.90). Apart from the metal chelating assay, there was a high correlation between the antioxidant activities of the extracts and their RACI values. Pearson correlation analysis showed that the correlation between the phenolic/flavonoid contents of the extracts and their antioxidant activities was over 0.9. The antioxidant activity of A. impudicus was brought to the literature for the first time with this study. When the data obtained from the current study were evaluated as a whole, it was concluded that S. imbricatus could be a rich source for new and alternative antioxidant compounds.

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Section: Chemical Compositions Of Mushroom Extractsmentioning

confidence: 51%

Chemical compositions and antioxidant activities of four different mushroom species collected from Turkey

Tepe

2021

International Journal of Secondary Metabolite

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“…This compound belongs to the class of cyclic polyols, an under-appreciated class of organic compounds, compared with aromatic (poly) phenolics [ 48 ]. Two main polysaccharide components (Ccp-I-A, Ccp-I-B) from the fruit bodies of C. comatus also have a strong antioxidant effect, whose scavenging activity on superoxide anions could reach 95% that of ascorbic acid [ 49 ]. Alkalic-extractable polysaccharides showed strong antioxidant and anti-inflammatory abilities as well as low hepatic lipid peroxidation levels in a model of alcohol-induced liver injury [ 50 ].…”

Section: Resultsmentioning

confidence: 99%

Chemical composition, nutritional profile and in vivo antioxidant properties of the cultivated mushroom Coprinus comatus

et al. 2020

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This study investigated the chemical and nutritional profile and antioxidative properties of cultivated Coprinus comatus . Proximate analysis revealed that C. comatus is rich in carbohydrates, dietary fibres and proteins, and could also be a valuable source of phenolics. Additionally, fat content is low, consisting mainly of polyunsaturated and omega-3 fatty acids. Furthermore, the safety profile of C. comatus is satisfactory, with all elements of toxicological importance within the proposed limits. Oral treatment with C. comatus for 42 days improved the antioxidant capabilities and ameliorated carbon tetrachloride-induced liver damage in rats, marked by decreased serum aminotransferase levels and lipid peroxidation intensity. Glutathione concentrations increased in a dose-dependent manner. Histological morphometric and immunohistochemical analysis confirmed antioxidative and hepatoprotective potential. These findings imply that cultivated C. comatus could be considered a nutraceutical, having beneficial nutrient and therapeutic properties.

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“…The content of phenolic compounds in C. comatus aqueous extract (Tešanovi c et al, 2017) (Cao et al, 2019).…”

Section: Nutritional Value and Chemical Composition Of CCmentioning

confidence: 99%

“…The highest DPPH (α‐diphenyl‐β‐picrylhydrazyl) radical scavenging capacity from of all tested CC fractions was ICPs (63.78 ± 0.38%) in 10 mg/mL concentration. The highest OH radical scavenging capacity in 10 mg/mL concentration reached ICPs with 91.85 ± 1.38 U/mL and ECPs with 84.95 ± 0.78 U/mL (Cao et al, 2019).…”

Section: The Positive Influence Of CC On the Human Healthmentioning

confidence: 99%

“…The all polysaccharides extracts of CC tested by Cao et al inhibit activity of α‐amylase at 2–10 mg/mL concentration. Extract called ICPs had the highest inhibitory effect on α‐amylase and reached 87.15 ± 0.99% (Cao et al, 2019). Polysaccharides from CC caused inhibition of nonenzymatic glycosylation that can limit diabetic complications, like macroangiopathy and microangiopathy.…”

Section: The Positive Influence Of CC On the Human Healthmentioning

confidence: 99%

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The two faces of Coprinus comatus—Functional properties and potential hazards

Nowakowski

Naliwajko

Markiewicz‐Żukowska

et al. 2020

Phytotherapy Research

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Mushrooms have been used for centuries not only as food but also in traditional medicine as a source of components with pro-health activity. One of them is Coprinus comatus (O.F.Müll.) Pers. also called shaggy mane, chicken drumstick mushroom, or lawyer's wig. In Asian countries, C. comatus (CC) is approved as edible mushroom and often cultivated for consumption, whereas in many other countries, although it is widespread, it is unrecognized and not used. In this review, for the first time, we discussed about the composition related to functional properties as well as the potential risks associated with consumption of CC by reviewing scientific literature. The information has been collected in order to get to know this species thoroughly. Various studies show many of the physiological activities, such as antioxidant, anticancer, antiandrogenic, hepatoprotective, acetylcholinesterase inhibitory, antiinflammatory, antidiabetic, antiobesity, antibacterial, antifungal, antinematode, and antiviral. Besides positive physiological properties, CC has also negative features, for example, skin reactions in patients with dermatitis and atopic predisposition, risk of confusion with poisonous mushrooms, quick autolysis after collection, and contamination of toxic elements.

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Comparative study on the monosaccharide compositions, antioxidant and hypoglycemic activities in vitro of intracellular and extracellular polysaccharides of liquid fermented Coprinus comatus

Cited by 55 publications

References 15 publications

Chemical compositions and antioxidant activities of four different mushroom species collected from Turkey

Chemical compositions and antioxidant activities of four different mushroom species collected from Turkey

Chemical composition, nutritional profile and in vivo antioxidant properties of the cultivated mushroom Coprinus comatus

The two faces of Coprinus comatus—Functional properties and potential hazards

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