Comparative study on the enantiomer separation of 1,1′-binaphthyl-2,2′diyl hydrogenphosphate and 1,1′-bi-2-naphthol by liquid chromatography and capillary electrophoresis using single and combined chiral selector systems

Chiral capillary electrophoresis: Facts and fiction on the reproducibility of resolution with randomly substituted cyclodextrins

“…The BNP-CD complex was extensively studied by the groups of Blaschke [11,12] and Kano [13][14][15]. The enantiomers were separated with various CDs, e.g., native [16,17] and sulfated CDs [18], heptakis(6-hydroxyethylamino-6-deoxy)-b-CD [19], maleic acid derivative of b-CD [20], CDs in combination with bile salts [21,22], and quaternary ammonium b-CDs in nonaqueous CE [23]. Separation was also performed with noncyclic saccharides, such as mono- [24], di- [25] and polysaccharides [26,27].…”

Chiral separations by capillary electrophoresis: Recent developments and applications

“…The most frequently used dual selectors are combinations of different CDs [109,110]. The use of CDs with chiral surfactants such as bile salts or polymeric surfactants was shown to improve resolution [6,97,111,112]. Mertzman and Foley [103] have combined for the first time CDs with MEEKC for the chiral separation of some basic drugs.…”

Perphenylcarbamoylated β‐cyclodextrin bonded‐silica particles as chiral stationary phase for enantioseparation by pressure‐assisted capillary electrochromatography

“…Moreover, CDs are themselves chiral, making them amenable for enantiomeric resolution. Accordingly, it is not surprising that CDs and their derivatives play an important role as chiral separation selectors in enantioselective chromatography [19][20][21][22][23][24][25][26]. Li and Lloyd [27] showed the separation of a series of compounds on a capillary packed with a b-CD stationary phase.…”