Comparative study on skin protection activity of polyphenol-rich extract and polysaccharide-rich extract from Sargassum vachellianum

Jesumani, Valentina; Du, Hong; Pei, Pengbing; Aslam, Muhammad; Huang, Nan

doi:10.1371/journal.pone.0227308

Cited by 58 publications

(38 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The photoprotective activity of polysaccharides rich extract from brown seaweeds ( Hizikia fusiforme, Sargassum fusiforme, Sargassum vachellianum, and Ecklonia maxima ) was investigated and monosaccharide analysis showed that most of its rich extract contains sulfate group and a high amount of fucose (43.20 to 53.53 %) ( Table 2 ). In addition, it was found that fucose-containing sulfated polysaccharides possessed various bioactivities and most of the polysaccharides rich extract were able to inhibit ROS production and down regulated MMP expression (especially MMP-1) [ 21 , 45 , 46 , 47 , 48 , 49 ]. This suggests that the anti-photoaging activity of polysaccharides rich extract from brown seaweeds was mainly mediated through antioxidant and MMP inhibitory activity.…”

Section: Seaweed Compounds As Potential Sources Of Anti-photoagingmentioning

confidence: 99%

“…Therefore, bioactive compounds from seaweeds ( Figure 1 and Figure 2 ) have attracted great interest and are known for promoting distinct functional activities of interest for the development of anti-photoaging products. They exhibit great ability in targeting several key players linked to anti-photoaging properties such as radical scavenging activity, strong UV absorption, inhibit cell death, MMP-1, and other activities [ 14 , 21 ]. This review focused on the anti-photoaging potential of seaweed-derived bioactive compounds and extracts.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Anti-Photoaging and Potential Skin Health Benefits of Seaweeds

2021

View full text Add to dashboard Cite

The skin health benefits of seaweeds have been known since time immemorial. They are known as potential renewable sources of bioactive metabolites that have unique structural and functional features compared to their terrestrial counterparts. In addition, to the consciousness of green, eco-friendly, and natural skincare and cosmetics products, their extracts and bioactive compounds such as fucoidan, laminarin, carrageenan, fucoxanthin, and mycosporine like amino acids (MAAs) have proven useful in the skincare and cosmetic industries. These bioactive compounds have shown potential anti-photoaging properties. Furthermore, some of these bioactive compounds have been clinically tested and currently available in the market. In this contribution, the recent studies on anti-photoaging properties of extracts and bioactive compounds derived from seaweeds were described and discussed.

show abstract

Section: Seaweed Compounds As Potential Sources Of Anti-photoagingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Anti-Photoaging and Potential Skin Health Benefits of Seaweeds

2021

View full text Add to dashboard Cite

show abstract

“…Production of high-quality purified fucoidans is urgently required to clarify the relationships between chemical structure and the various bioactivities attributed to fucoidans, eliminating any interference from contaminants. However, it was observed in some cases that crude extracts and presence of co-extracted contaminants, especially polyphenolic phlorotannins, have advantageous cosmeceutical effects due to their powerful anti-oxidant activity [203,204].…”

Section: Conclusion and Future Prospectivementioning

confidence: 99%

Fucoidans: Downstream Processes and Recent Applications

Zayed

Ulber

2020

Marine Drugs

View full text Add to dashboard Cite

Fucoidans are multifunctional marine macromolecules that are subjected to numerous and various downstream processes during their production. These processes were considered the most important abiotic factors affecting fucoidan chemical skeletons, quality, physicochemical properties, biological properties and industrial applications. Since a universal protocol for fucoidans production has not been established yet, all the currently used processes were presented and justified. The current article complements our previous articles in the fucoidans field, provides an updated overview regarding the different downstream processes, including pre-treatment, extraction, purification and enzymatic modification processes, and shows the recent non-traditional applications of fucoidans in relation to their characters. of 22reproductive, immune and cell-to-cell communicative roles [23]. As recommended by the International Union of Pure and Applied Chemistry (IUPAC), fucoidans is a general term used to describe sulfated L-fucose-based polymers including sulfated fucans cited by the Swedish scholar Kylin, as well as other fucose-rich sulfated heteropolysaccharides [23,28]. Their chemical structures, in terms of monomeric composition and branching, are quite simple in marine invertebrates compared to their analogues in brown algae [13,29].Hundreds of articles have thoroughly discussed and reviewed the biological, pharmacological and pharmaceutical applications of fucoidans [30][31][32][33], including nanomedicine, [34] which has made it a hot topic in the last few decades [35][36][37]. All these studies tried to investigate fucoidans molecular mechanisms in relation to their chemical structure and physicochemical properties. Therefore, different hypotheses were suggested for each activity, such as anti-tumor [31,[38][39][40], anti-coagulant [41,42], anti-viral [43,44] and anti-inflammatory activity [45,46]. These investigations revealed that various factors are relevant, such as molecular weight, sulfation pattern, sulfate content and monomeric composition [47][48][49]. For example, different fractions were produced with different physicochemical properties in our previous experiments; sulfation pattern and sulfate content were highly related to anti-viral and cytotoxic activities against HSV-1 and Caco-2 cell lines, respectively, while molecular weight and sugar composition were potential factors in anti-coagulation activity [41,50]. In addition, degree of purity was reported as an influential factor [32], where co-extracted contaminants (e.g., phlorotannins or polyphenols) could lead to significant interference in anti-oxidant activity and, consequently, cosmetic applications [51,52].Therefore, several key production challenges regarding fucoidans were discussed in our last review article in order to obtain a product that follows the universal good manufactured practice (GMP) guidelines. The article discussed sources of heterogeneity in extracted fucoidans, including the different biotic (e.g., biogenic, geographical and seas...

show abstract

“…SPS showed considerable inhibition of tyrosinase (51.21%) and had better moisture absorption (52.1%) and retention (63.24%) abilities than SPP. 113 (4Z,9Z)-4-Methyl- 1,2,6,8-tetraazacycloundeca-4,9-diene-3,7,11-trione 164 is an eleven-membered macrocyclic hydrazide detected in S. vachellianum collected in the South China Sea (Fig. 10).…”

Section: Sargassum Vachellianummentioning

confidence: 99%