Comparative study on preoperative localization techniques using microcoil and hookwire by propensity score matching

Abstract

Background: The purpose of this study was to compare the efficacy and safety of two preoperative pulmonary nodule localization techniques using microcoil and hookwire. Methods: A total of 307 patients with 324 pulmonary nodules were included in the study from March 2012 to October 2016 in two medical centers. Baseline data, positioning operation data, success rate, complications, surgery and pathological results were statistically analyzed. Complications were used as the dependent variables, whereas others were used as covariates for the propensity score matching of the two groups. Statistical analyses were performed to compare the success rate and complication rate of the matched groups. Results: There were 218 lesions in the microcoil group and 106 nodules in the hookwire group. There were no significant differences in gender, age and the location of nodules between the two groups. The diameters of the nodules were smaller (8.2 AE 3.5 mm vs. 10.7 AE 4.3 mm) and solid nodules were fewer (11.5% vs. 26.4%) in the microcoil group. The complication rate of the two groups was not statistically significant. After propensity score matching, 71 patients in each group were successfully matched. We found that the success rate was higher (97.2% vs. 94.4%) and the incidence of complications was lower (31% vs. 15.5%) in the microcoil group. Conclusions: Both techniques have been shown to be effective in preoperative localization of tiny pulmonary nodules. The method of microcoil localization has more advantages in clinical application. Key pointsComparison of the efficacy and safety of two methods in preoperative pulmonary nodule localization in order to determine the optimal method.

Comparison of hook-wire and medical glue for CT-guided preoperative localization of pulmonary nodules

“…Several methods have been reported for pre-operative localization of pulmonary nodules, including intraoperative ultrasound ( 7 , 8 ), hook-wire localization ( 9 , 10 ), medical glue ( 11 ), micro-coil ( 12 ), methylene blue ( 13 ), indocyanine green ( 14 ), or radionuclides ( 15 ), some with 100% localization success rate ( 16 ). Pneumothorax or parenchymal hemorrhage are common complications during pre-operative localization, while fatal consequences are rarely reported ( 17 , 18 ).…”

The incidence and risk factors of acute pain after preoperative needle localization of pulmonary nodules: a cross-sectional study

“…A retrospective study involving 57 patients reported that the incidence of pain after hookwire localization was 7%, but they did not clearly state the method used to assess pain nor at which state (13). Other studies assessed pain as the exploratory component of complications after hookwire localization (14,15), but the severity and related risk factors are still limited. Exploring potential predictors may be helpful to prevent acute pain in high-risk population.…”

A novel technique for preoperative localization of pulmonary nodules using a mixture of tissue adhesive and iohexol under computed tomography guidance: A 140 patient single‐center study

“…Preoperative CT‐guided localization has been widely used to mark pulmonary nodules. Both solid and liquid materials, such as hookwires, 9‐14 lipiodol, 15 microcoils, 12,16,17 dye 17,18 and radiotracers 19 have been developed as localization markers. We summarized the literature on preoperative localization techniques with sample numbers >100 and other similar studies published within the last five years, 11,20‐25 and compared the results with ours (Table 4 ) .…”