Comparative Study on Nigerian Wild and Edible Beans in Reversing Incidence of Colon Cancer in Albino Rats

Abstract

This work is an investigation of the curative effects of some edible and wild type beans on colonic inflammation induced by Dextran Sulphate Sodium (DSS) in wister albino rats. Macroscopic examination performed on the colon after seven-day exposure of the animals to both DSS and bean sample revealed a high incidence of colonic inflammation in rats fed with macuna compared to other groups. However, from the histological examination, the groups fed with Otili and Feregede had a low incidence of dysplasia showing Otili and Feregede to be good candidates that could mitigate effect of Dextran Sodium Sulphate.

<i>In-Vitro</i> Metabolite Colonic Production from Otili (<i>Sphenostylis stenocarpa</i>) as Influenced by Selected Gastrointestinal Microbes

“…Some of our studies made so far include assessment of the functional properties, nutritional qualities and scavenging ability of the Otili-wild beans [13] [14] [15]. Data provided preliminary evidence that consumption of beans diet such as the Nigerian wild-Otili (Sphenostylis stenocarpa) competed favorably with the common edible bean Phaseolus vulgaris in bioactive compounds constituents.…”