Comparative Study on Doxorubicin Loaded Metallic Nanoparticles in Drug Delivery Against MCF-7 Cell Line

Alagu, Thirumurugan; Vijayakumar, B.; Karthikeyan, M.

doi:10.1016/b978-0-08-101971-9.00011-9

Cited by 7 publications

(3 citation statements)

References 28 publications

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“…Thirumurugan et al 40 reported the biological synthesis of noble-metal NPs (Pt and Ag NPs) using curry leaves and neem extracts. Doxorubicin (DOX), an anticancer drug, was encapsulated in synthesized NPs and its in vitro study was assessed against MCF-7 cell lines.…”

Section: Resultsmentioning

confidence: 99%

“…In addition, the efficiency of functionalized 3-mercaptopropionic acid-capped Au NPs in drug delivery against K562/ADM cells was evaluated by Li and co-workers. 39 Thirumurugan et al 40 reported the biological synthesis of noble-metal NPs (Pt and Ag NPs) using curry leaves and neem extracts. Doxorubicin (DOX), an anticancer drug, was encapsulated in synthesized NPs and its in vitro study was assessed against MCF-7 cell lines.…”

Section: Acs Omegamentioning

confidence: 99%

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Green Nanotechnology-Driven Drug Delivery Assemblies

et al. 2019

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Green nanotechnology incorporates the principles of green chemistry and green engineering to fabricate innocuous and eco-friendly nanoassemblies to combat the problems affecting the human health or environment. Subsequently, amalgamation of green nanotechnology with drug delivery area has actually commenced a new realm of “green nanomedicine”. The burgeoning demand for green nanotechnology-driven drug delivery systems has led to the development of different types of delivery devices, like inorganic (metallic) nanoparticles, quantum dots, organic polymeric nanoparticles, mesoporous silica nanoparticles, dendrimers, nanostructured lipid carriers, solid lipid nanoparticles, etc. The present article deals with a brief account of delivery devices produced from green methods and describes site-specific drug delivery systems (including their pros and cons) and their relevance in the field of green nanomedicine.

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Section: Resultsmentioning

confidence: 99%

Section: Acs Omegamentioning

confidence: 99%

Green Nanotechnology-Driven Drug Delivery Assemblies

et al. 2019

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“…These efforts are continuing since most cancer cells have developed resistance to doxorubicin. By using curry leaves and neem extracts, Thirumurugan et al [ 241 ] formulated Pt NPs and Ag NPs with encapsulated Doxorubicin (Dox). In vitro tests with MCF-7 cell lines revealed that a better inhibition value (IC 50 ) against MCF-7 demonstrated Dox-coated Ag NPs than Dox-coated Pt NPs.…”

Section: Therapy and Drug Delivery Of Biosynthesized Npsmentioning

confidence: 99%

Updates on Biogenic Metallic and Metal Oxide Nanoparticles: Therapy, Drug Delivery and Cytotoxicity

Nikolova

Joshi²,

Chavali

2023

Pharmaceutics

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The ambition to combat the issues affecting the environment and human health triggers the development of biosynthesis that incorporates the production of natural compounds by living organisms via eco-friendly nano assembly. Biosynthesized nanoparticles (NPs) have various pharmaceutical applications, such as tumoricidal, anti-inflammatory, antimicrobials, antiviral, etc. When combined, bio-nanotechnology and drug delivery give rise to the development of various pharmaceutics with site-specific biomedical applications. In this review, we have attempted to summarize in brief the types of renewable biological systems used for the biosynthesis of metallic and metal oxide NPs and the vital contribution of biogenic NPs as pharmaceutics and drug carriers simultaneously. The biosystem used for nano assembly further affects the morphology, size, shape, and structure of the produced nanomaterial. The toxicity of the biogenic NPs, because of their pharmacokinetic behavior in vitro and in vivo, is also discussed, together with some recent achievements towards enhanced biocompatibility, bioavailability, and reduced side effects. Because of the large biodiversity, the potential biomedical application of metal NPs produced via natural extracts in biogenic nanomedicine is yet to be explored.

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Structure and Rheology of Hydrogels: Applications in Drug Delivery

Marapureddy

Thareja

2020

Biointerface Engineering: Prospects in Medical Diagnostics and Drug Delivery

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Comparative Study on Doxorubicin Loaded Metallic Nanoparticles in Drug Delivery Against MCF-7 Cell Line

Cited by 7 publications

References 28 publications

Green Nanotechnology-Driven Drug Delivery Assemblies

Green Nanotechnology-Driven Drug Delivery Assemblies

Updates on Biogenic Metallic and Metal Oxide Nanoparticles: Therapy, Drug Delivery and Cytotoxicity

Structure and Rheology of Hydrogels: Applications in Drug Delivery

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