Comparative Study on Antioxidative Activity of Glycyrrhiza uralensis and Glycyrrhiza glabra Extracts by Country of Origin

Abstract

In this work, comparative study on antioxidative activities of extracts from Glycyrrhiza uralensis (G. uralensis) produced in Korea and in China and Glycyrrhiza glabra (G. glabra) produced in Uzbekistan was conducted. Among three origins, 50% ethanol extracts (21.15 µg/mL), ethyl acetate fraction (29.15 µg/mL) and aglycone fraction (3.26 µg/mL) of G. uralensis from Korea showed the higher free radical (1,1-phenyl-2-picrylhydrazyl, DPPH) scavenging activity (FSC50) than extracts from other origins. Reactive oxygen species (ROS) scavenging activities (OSC50) of extracts from three origins on ROS generated in Fe 3+-EDTA/H2O2 system were investigated using luminol-dependent chemiluminescence assay 50% ethanol extract (1.00 µg/mL) and ethyl acetate fraction (0.34 µg/mL) of G. uralensis from China showed the most prominent ROS scavenging activity. The protective effects of extract/fractions of G. uralensis and G. glabra extracts on the rose-bengal sensitized photohemolysis of human erythrocytes were investigated. 50% ethanol extract and aglycone fraction of G. uralensis and G. glabra extracts from three origins showed cellular protective effects in a concentration dependent manner (5 ∼ 50 µg/mL). Aglycone fraction of G. uralensis from Korea (τ50 = 847.4 1) † 주 저자

Antioxidant and Antibacterial Activities of Glycyrrhiza uralensis Fisher (Jecheon, Korea) Extracts Obtained by various Extract Conditions

“…본 연구에 앞서 저자들은 국내산 농산물의 수입대체 목적으로 국가별(한국, 중국 및 우즈베키스탄) 감초의 항산화 활성을 비교 분석하여 보고한 바 있다. 한국 감 초 추출물의 분획별 항산화 활성을 측정한 결과 수입 된 중국 및 우즈베키스탄 감초보다 라디칼 소거활성 과 활성산소에 대한 세포보호효과가 매우 탁월함을 확인하였다 [15]. 또한 원산지별 감초 추출물에 대하여 피부 상재균(Staphylococcus aureus, Bacillus subtilis, Propionibacterium acnes, Escherichia coli, Pseudomonas aeruginosa 및 Pityrosporum ovale)에 대한 항균 활성을 측정 비교하였다.…”

Licoricidin, an isoflavonoid isolated from Glycyrrhiza uralensis Fisher, prevents UVA‐induced photoaging of human dermal fibroblasts

“…Licorice plants belong to the legume family and are widely used in plant‐based medicinal treatments in South Korea, China and Japan. In a previous study, it was reported that licorice extracts from South Korea had higher anti‐oxidative activity than those of China and Uzbekistan . They also had potent anti‐microbial effects that were attributed to their ability to stabilize a medicinal cream .…”

Enhanced skin delivery of liquiritigenin and liquiritin‐loaded liposome‐in‐hydrogel complex system

“…Liquiritigenin and its glycoside liquiritin are known to main components among the flavonoids [5][6][7]. Licorice flavonoids have been widely used as antioxidants in cosmetics.…”

“…Licorice flavonoids have been widely used as antioxidants in cosmetics. Liquiritigenin and its glycoside liquiritin are known to main components among the flavonoids [5][6][7]. However, applications of these flavonoids for cosmetics are limited because they are unstable to light or heat and almost insoluble in water [8].…”