Comparative study on antimicrobial activity of Sambucus spp. plant extracts

Rodino, Steliana; Buţu, Marian; Negoescu, Constanta; Condei, R.; Niculae, Ioana; Buţu, Alina; Cornea, Călina Petruţa

doi:10.1016/j.jbiotec.2015.06.041

Cited by 7 publications

(11 citation statements)

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Section: Antibacterial Activitymentioning

confidence: 99%

“…Most of the pharmacological actions of GA also include antimicrobial activity through the inhibition of bacterial infection by decreasing the expression of genes, inhibiting bacte-rial growth, and reducing the production of microbial toxins [42][43][44][45]. Several approaches have shown that GA has potent effects in inhibiting the activities of Gram-positive bacteria and Gram-negative bacteria [42][43][44][45]. Chung et al (1998) reported, for the first time, the effect of GA on the inhibition of arylamine N-acetyltransferase (NAT) activities, substrates determined in Helicobacter pylori, and consequently, the GA inhibition of growth in the bacterium H. pylori [42].…”

Section: Antibacterial Activitymentioning

confidence: 99%

“…These genes regulate the production of numerous virulence factors, including hemolysins, leukotoxins, and adhesins [44]. The alcoholic extract from the roots of G. glabra showed a significant antibacterial activity, developing areas of growth inhibition against Staphylococcus aureus, Escherichia coli, Pseudomonas fluorescens, and Bacillus cereus [45]. Yoshida et al (2010) investigated the effects of GA on Pseudomonas aeruginosa.…”

Section: Antibacterial Activitymentioning

confidence: 99%

“…[44] Antibacterial GA showed a significant antibacterial activity against S. aureus, E. coli, P. fluorescens, and Bacillus cereus. [45] Antibacterial GA increased the eradication rate of H. pylori in patients with gastrointestinal disorders. [60][61][62] Antioxidant GA were able to increase the intracellular reduced glutathione concentration, in AFB1-treated cells.…”

Section: Antiviralmentioning

confidence: 99%

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Exploring the Pharmacological Potential of Glycyrrhizic Acid: From Therapeutic Applications to Trends in Nanomedicine

Nascimento

Araújo

2022

Future Pharmacology

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Glycyrrhizic acid (GA) is the main active component of the licorice root, which has been known in traditional medicine since the ancient times. It is a molecule composed of a hydrophilic part, two glucuronic acid molecules, and a hydrophobic part, glycyrrhetinic acid. GA, when subjected to acid hydrolysis, releases 18β- and 18α-glycyrrhetinic acids. Glycyrrhetinic acid is most responsible for the pharmacological activities of licorice. GA has been reported to have multiple therapeutic properties: anti-viral, anti-inflammatory, antitumor, antimicrobial and hepatoprotective. Different approaches have revealed similar anti-inflammatory mechanisms of action of GA, such as the inhibition of translocation of nuclear factor-κB (NF-κB) and suppression of Tumour Necrosis Factor alpha (TNF-α) and interleukins. In this sense, several in vitro and in vivo studies have described the use of GA in the prevention and treatment of several complications, especially microbial/viral infection, and as a novel chemo-preventive agent for liver injury. Recent studies postulated that GA nanoparticles (GANPs) can be a promising strategy for the treatment of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infections. This mini-review summarizes the pharmacological activities of GA and its beneficial effects against various health problems and provides perspectives on the development of versatile nanoplatforms to overcome some limiting physicochemical properties and for enhancing the therapeutic benefits of GA.

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Section: Antibacterial Activitymentioning

confidence: 99%

Section: Antibacterial Activitymentioning

confidence: 99%

Section: Antibacterial Activitymentioning

confidence: 99%

Section: Antiviralmentioning

confidence: 99%

See 2 more Smart Citations

Exploring the Pharmacological Potential of Glycyrrhizic Acid: From Therapeutic Applications to Trends in Nanomedicine

Nascimento

Araújo

2022

Future Pharmacology

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“…Penelitian ini sejalan dengan hasil penelitian Rodino dkk. [23] yang mengungkapkan bahwa ekstrak etanol dari tanaman akar manis dapat menghambat pertumbuhan bakteri Bacillus cereus dengan aktivitas zona hambat 15 mm. Fraksi etil asetat memiliki zona hambat terbesar dibandingkan dengan fraksi yang lainnya, sehingga fraksi etil asetat akar manis dilanjutkan ketahap identifikasi senyawa bioktif menggunakan instrumen GCMS.…”

Section: Penentuan Aktivitas Antibakteriunclassified

Potential of Antibacterial Compounds from Sweet Root Extract (Glycyrrhiza glabra L) on Bacillus cereus

2019

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The high number of poisoning food and diarrheal diseases caused by Bacillus cereus bacteria has been treated with chemical drugs and traditionally herbal plants. One of the commonly used herbal plants is sweet root (Glycyrrhiza glabra L.). This study aims to extract and fractionate sweet root plants, determine the antibacterial activity and identify the types of bioactive compounds as antibacterial compounds. The extraction process uses a maceration technique and fractionation using buthanol, ethyl acetate, and hexan solvents. Antibacterial activity was carry out by the diffusion method and identification of bioactive compounds by GCMS analysis. This study showed that greatest antibacterial activity was found in ethyl acetate fraction with a strong category and MIC value of 12,5%. This study for the first time also revealed that the types of bioactive compounds from sweet root plants (Glycyrrhiza glabra L.) as antibacterial compounds are n-Hexadecanoic as a fatty acid group and 4H-Pyran 4-one 2.3 dihydro-3, 5-dihydroxy-6 methyl from the flavonoid group.

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Xuanfei Baidu decoction in the treatment of coronavirus disease 2019 (COVID-19): Efficacy and potential mechanisms

Meng,

Ding,

Shen

et al. 2023

Heliyon

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Comparative study on antimicrobial activity of Sambucus spp. plant extracts

Cited by 7 publications

References 0 publications

Exploring the Pharmacological Potential of Glycyrrhizic Acid: From Therapeutic Applications to Trends in Nanomedicine

Exploring the Pharmacological Potential of Glycyrrhizic Acid: From Therapeutic Applications to Trends in Nanomedicine

Potential of Antibacterial Compounds from Sweet Root Extract (Glycyrrhiza glabra L) on Bacillus cereus

Xuanfei Baidu decoction in the treatment of coronavirus disease 2019 (COVID-19): Efficacy and potential mechanisms

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