Comparative Study of Videolaryngostroboscopic Findings and Voice Handicap Index Before and After Treatment in Patients Presenting with Hoarseness Due to Non Malignant Lesions

Itigi, Sphoorthy G.; Sikdar, Abhik; Phatak, Shrikant; Nivsarkar, Sameer

doi:10.1007/s12070-021-03047-0

Cited by 1 publication

(1 citation statement)

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“…The use of LVS for organic lesions has been established by previous research in this area (El-Demerdash et al 2015 ; Rzepakowska et al 2017 ; Itigi et al 2022 ). Unfortunately, this technique is susceptible to failure in some of the vocal fold organic masses, as it requires synchronization of strobe light with the fundamental frequency of the patient’s voice.…”

Section: Introductionmentioning

confidence: 99%

Value of high-speed videoendoscopy as an auxiliary tool in differentiation of benign and malignant unilateral vocal lesions

Malinowski,

Pietruszewska,

Kowalczyk

et al. 2024

J Cancer Res Clin Oncol

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Purpose The study aimed to assess the relevance of objective vibratory parameters derived from high-speed videolaryngoscopy (HSV) as a supporting tool, to assist clinicians in establishing the initial diagnosis of benign and malignant glottal organic lesions. Methods The HSV examinations were conducted in 175 subjects: 50 normophonic, 85 subjects with benign vocal fold lesions, and 40 with early glottic cancer; organic lesions were confirmed by histopathologic examination. The parameters, derived from HSV kymography: amplitude, symmetry, and glottal dynamic characteristics, were compared statistically between the groups with the following ROC analysis. Results Among 14 calculated parameters, 10 differed significantly between the groups. Four of them, the average resultant amplitude of the involved vocal fold (AmpInvolvedAvg), average amplitude asymmetry for the whole glottis and its middle third part (AmplAsymAvg; AmplAsymAvg_2/3), and absolute average phase difference (AbsPhaseDiffAvg), showed significant differences between benign and malignant lesions. Amplitude values were decreasing, while asymmetry and phase difference values were increasing with the risk of malignancy. In ROC analysis, the highest AUC was observed for AmpAsymAvg (0.719; p < 0.0001), and next in order was AmpInvolvedAvg (0.70; p = 0.0002). Conclusion The golden standard in the diagnosis of organic lesions of glottis remains clinical examination with videolaryngoscopy, confirmed by histopathological examination. Our results showed that measurements of amplitude, asymmetry, and phase of vibrations in malignant vocal fold masses deteriorate significantly in comparison to benign vocal lesions. High-speed videolaryngoscopy could aid their preliminary differentiation noninvasively before histopathological examination; however, further research on larger groups is needed.

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Section: Introductionmentioning

confidence: 99%