Comparative study of two models predicting the risk of deep vein thrombosis progression in spinal trauma patients after operation

Lai, Jiaxin; Wu, Shiyang; Fan, Ziwei; Jia, Mengxian; Yuan, Zongjie; Yan, Xin; Teng, Honglin; Zhuge, Linmin

doi:10.1016/j.clineuro.2023.108072

Cited by 4 publications

(1 citation statement)

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“…Routine blood tests, which measure RBC and white blood cell(WBC) counts, hemoglobin levels, and platelet counts, might enhance current risk assessment models for thromboembolic diseases [ 7 ]. Studies have found correlations between these hematological parameters and DVT risk formation in various patient populations [ 8 ], including those with fibromyalgia and individuals undergoing spinal surgery, highlighting the importance of coagulation function tests in diagnosing thromboembolic conditions [ 9 – 11 ].…”

Section: Introductionmentioning

confidence: 99%

Associations of RBC counts and incidence of DVT in patients with spinal cord injury: a five year observational retrospective study

Jinlong,

Cheng,

Chengqi

2024

J Orthop Surg Res

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Background The role of red blood cell (RBC) counts as potential independent risk factors for deep vein thrombosis (DVT) in patients with spinal cord injury (SCI) remains uncertain. This study aims to clarify the associations between RBC counts and DVT incidence among this population. Methods A retrospective analysis was performed on 576 patients with SCI admitted to the rehabilitation medicine department from January 1, 2017 to December 31, 2021. After exclusions, 319 patients were analyzed, among which 94 cases of DVT were identified. Results Mode of injury, D-dimer and anticoagulant therapy were significant covariates (P < 0.05). Age, fibrinogen, D-dimer, anticoagulant therapy and American Spinal Cord Injury Association impairment scale (AIS) grades were associated with RBC counts and DVT incidence (P < 0.05). Adjusting for these factors, a 1.00 × 10^12/L increase in RBC counts correlated with a 45% decrease in DVT incidence (P = 0.042), revealing a “U” shaped relationship with a pivot at 4.56 × 10^12/L (P < 0.05). Conclusion RBC counts below 4.56 × 10^12/L serve as a protective factor against DVT, while counts above this threshold pose a risk. These findings could inform the development of DVT prevention strategies for patients with SCI, emphasizing the need for targeted monitoring and management of RBC counts.

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