Comparative study of tramadol and ketorolac in the pain management of third molar tooth extraction

Shaik, Munvar Miya; Kumar, Jatin; Mobina, S; Satyanarayana, N; Sunitha, P

doi:10.3126/jcmsn.v6i1.3600

Cited by 8 publications

(6 citation statements)

References 8 publications

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“…108 Tramadol usage has also been suggested in many studies as an efficient pain reliever after third molar surgeries. 109,110 However, not only combination analgesics have been reported to enhance pain relief. Additionally, corticosteroids can also help.…”

Section: Treatment For Acute Painmentioning

confidence: 99%

Pain in Oral and Maxillofacial Surgery and Implant Dentistry: Types and Management

et al. 2021

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Over the years, the pain has been defined numerous times in several ways. In oral and maxillofacial surgery, the occurrence of pain, especially postoperatively, is anticipated. Pain arises as a combination of various processes after tissue damage. Distinct pain experiences in oral surgery were depicted in several previous studies, adding knowledge to the field. The management of these encounters has been suggested over time, improving treatment approaches in the clinical setting. This review aims to understand the pain and its types and intervention in the field of oral and maxillofacial surgery.

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Section: Treatment For Acute Painmentioning

confidence: 99%

Pain in Oral and Maxillofacial Surgery and Implant Dentistry: Types and Management

et al. 2021

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“…(16) Tramadol is a suitable and safe analgesic for the relief of post extraction pain and is more effective than Ketorolac . (8) In this study, PS was superior and significant compared to post operative analgesia and control. This can be explained by the fact that the analgesic effect of Tramadol before the nociceptive stimuli was more effective than the same dose given later and that the effect of pre-emptive analgesia was to prevent or reduce the development of any "memory" of pain stimulation in the nervous system.…”

Section: Discussionmentioning

confidence: 54%

“…(7) The risk of respiratory depression is significantly lower at equianalgesic doses and does not depress the hypoxic ventilatory response, and does not increase seizure incidence when compared to other analgesic agents. (8) The aim of the present study was to estimate the anti-nociceptive effect of Tramadol by the use of preoperative Tramadol injection and compare it to post operative analgesia initiated compared to placebo.…”

Section: Anti-nociceptive Efficacy Of Tramadol Following Surgical Remmentioning

confidence: 99%

Anti–Nociceptive Efficacy of Tramadol Following Surgical Removal of Impacted Mandibular Third Molar

Al–Sandook¹

2012

RDENTJ

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Aims of the Study: To evaluate the efficacy of analgesia mediated by preoperative 100 mg IM Tramadol to the post operative Tramadol and placebo after the surgical removal of mandibular wisdom tooth. Materials and Methods: Surgical removal of mandibular third molar was performed in three groups of individuals, total of thirty patients were anticipated in this study. All medically fit, average of age 24 + 2.2; each group consisted of ten patients. Group 1: Preoperative 100 mg Tramadol IM injection 30 minutes prior surgical operation; Group 2: Post operative 100 mg Tramadol IM injection; Group 3: Placebo or control group where distilled water IM injection was applied. All patients received post operatively Augmentin capsules 675 mg tid, and supplementary Paracetamol 500 mg tablet as required. Analgesia was assessed by Visual Analog Scale (VAS) and Verbal Pain Scale (VPS), patient satisfaction (PS), duration of post operative analgesia and total number of analgesic tablet were recorded between groups. Results: Analgesia mediated by Tramadol was superior in its efficacy compared to control group in both pre and post operative Tramadol groups, according to VAS and VPS assessment (p= 0.001). There was no significant difference between the preoperative and post operative analgesia according to VAS and VPS; whereas there was a significant difference in PS, and duration of analgesia mediated by the preoperative injection in comparison to the post operative and control groups. Conclusion: Preoperative Tramadol analgesia was superior to post operative analgesia in PS and prolonged duration of analgesia that explain its anti-nociceptive effect in controlling post surgical pain.

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“…This study showed a concurrent result with previous studies of tramadol. [ 10 11 12 13 14 ] In this study, aceclofenac + paracetamol also showed efficacy less than lornoxicam + paracetamol and tramadol + paracetamol but with better efficacy than ketorolac.…”

Section: Discussionmentioning

confidence: 67%

Efficacy of Routinely Used Analgesics in Management of Pulpal Pain Postoperatively a Clinical Study

Thota

Bansal

Thota

et al. 2021

Journal of Pharmacy and Bioallied Sciences

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Aim: The aim of this study was to evaluate the efficacy of various routinely used analgesics in the management of pulpal pain preoperatively. Materials and Methods: A total of 150 patients were randomly selected and divided into five groups each. At initial visit, a self-administered questionnaire was given, and patients were asked to mark on the Visual Analog Scale (VAS) indicating severity of pain at that moment which is taken as a pretreatment VAS score. Group I patients received aceclofenac + paracetamol, Group II: ketorolac tromethamine, Group III: lornoxicam + paracetamol, Group IV: tramadol + paracetamol, and Group V: paracetamol. All the patients are requested to record their pain levels at 4 h, 6 h, 8 h, 24 h, and 48 h by means of VAS scores before and after treatment. Results: There was no significant decrease in frequency of pain when compared in the first three groups, whereas in Group III and Group IV, the patients experienced an effective reduction in pain because of sustained releasing ability of these drugs. Overall, there was no statistically significant differences among all the groups. Conclusion: This study suggests that there was no significant difference in reduction of pain preoperatively. However, lornoxicam + paracetamol and tramadol + paracetamol were effective because of their sustained releasing ability. Ketorolac was effective to reduce the pain for shorter duration. Paracetamol can be advised in compromised patients where safety is concerned.

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Comparative study of tramadol and ketorolac in the pain management of third molar tooth extraction

Cited by 8 publications

References 8 publications

Pain in Oral and Maxillofacial Surgery and Implant Dentistry: Types and Management

Pain in Oral and Maxillofacial Surgery and Implant Dentistry: Types and Management

Anti–Nociceptive Efficacy of Tramadol Following Surgical Removal of Impacted Mandibular Third Molar

Efficacy of Routinely Used Analgesics in Management of Pulpal Pain Postoperatively a Clinical Study

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