Comparative Study of the Lower Limb Muscle Tone under the Conditions of Five-day Support Unloading Coupled with Different Regimens of Electromyostimulation

Amirova, Liubov; Osetskiy, N. Yu.; Shishkin, Nikita; Пономарев, И. И.; Rukavishnikov, Ilya; Kozlovskaya, I. B.; Tomilovskaya, Elena

doi:10.1134/s0362119720040027

Cited by 3 publications

(3 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Also, it important to note that the time outside the immersion bath for women did not exceed that for men ( Treffel et al, 2017 ; Amirova et al, 2020a ). This is a good achievement as it is known that increasing the time outside the bath reduces the effects of DI ( Navasiolava et al, 2011 ).…”

Section: Discussionmentioning

confidence: 99%

The First Female Dry Immersion (NAIAD-2020): Design and Specifics of a 3-Day Study

et al. 2021

View full text Add to dashboard Cite

This article describes procedures and some results of the first study of females undergoing 3-day Dry Immersion. The experiment “NAIAD-2020” was carried out at the Institute of Biomedical Problems (Moscow, Russia) with the participation of six healthy women volunteers (age 30.17 ± 5.5 years, height 1.66 ± 0.1 m, weight 62.05 ± 8.4 kg, BMI 22.39 ± 2.2 kg/m2) with a natural menstrual cycle. During the study, a standard protocol was used, the same as for men, with a minimum period of time spent outside the immersion bath. Before, during and after Immersion, 22 experiments were carried out aimed at studying the neurophysiological, functional, metabolic and psychophysiological functions of the body, the results of which will be presented in future publications. The total time outside the bath for women did not exceed that for men. Systolic and diastolic pressure did not significantly change during the immersion. In the first 24 h after the end of the immersion, heart rate was significantly higher than the background values [F(4,20) = 14.67; P < 0.0001]. Changes in body temperature and water balance were consistent with the patterns found in men. No significant changes in height and weight were found during immersion. All women reported general discomfort and pain in the abdomen and back. The results of this study did not find significant risks to women’s health and showed the feasibility of using this model of the effects of space flight in women of reproductive age.

show abstract

Section: Discussionmentioning

confidence: 99%

The First Female Dry Immersion (NAIAD-2020): Design and Specifics of a 3-Day Study

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Nowadays women participate in space flights (SF) alongside men, and the differences between the sexes should be considered when training crewmembers for space missions. For many years space physiology studies have been conducted with male volunteers ( Kozlovskaya and Kirenskaya, 2004 ; Koppelmans et al, 2015 , 2017 ; De Abreu et al, 2017 ; Amirova et al, 2020 ), which was the “gold standard” of research, and was reasonable at the dawn of manned space exploration. However, physiological changes triggered in the female body by microgravity have been insufficiently investigated, and this may lead to both employment and casual discrimination of female astronauts.…”

Section: Introductionmentioning

confidence: 99%

“…Preventing and predicting motor impairments caused by weightlessness is especially significant for increasing SF duration and expanding the scope of motor tasks performed during space missions. The complex of changes occurring in human motor function under the conditions of real or simulated microgravity is called hypogravitational motor syndrome ( Kozlovskaya et al, 1988 ), and it is defined by a deficit in vestibular, proprioception, and support afferent activity ( Pechenkova et al, 2019 ), and substantial alterations in the functional (e.g., atony, a decline in speed-force qualities) and structural (e.g., atrophy and a phenotype deterioration) characteristics of skeletal muscles ( Kozlovskaya et al, 1988 ; Kozlovskaya and Kirenskaya, 2004 ; Koppelmans et al, 2017 ; Amirova et al, 2020 ). In experiments with animal models it was also shown that a hindlimb suspension in rats results in nerve fiber demyelinization, which in turn may play a role in the development of hypogravitational motor syndrome ( Islamov et al, 2013 ).…”

Section: Introductionmentioning

confidence: 99%

NAIAD-2020: Characteristics of Motor Evoked Potentials After 3-Day Exposure to Dry Immersion in Women

Nosikova

Riabova

Amirova

et al. 2021

Front. Hum. Neurosci.

View full text Add to dashboard Cite

As female astronauts participate in space flight more and more frequently, there is a demand for research on how the female body adapts to the microgravity environment. In particular, there is very little research on how the neuromuscular system reacts to gravitational unloading in women. We aimed to estimate changes in motor evoked potentials (MEPs) in the lower leg muscles in women after 3-day exposure to Dry Immersion (DI), which is one of the most widely used ground models of microgravity. Six healthy female volunteers (mean age 30.17 ± 5.5 years) with a natural menstrual cycle participated in this experiment. MEPs were recorded from the gastrocnemius and soleus muscles twice before DI, on the day of DI completion, and 3 days after DI, during the recovery period. To evoke motor responses, transcranial and trans-spinal magnetic stimulation was applied. We showed that changes in MEP characteristics after DI exposure were different depending on the stimulation site, but were similar for both muscles. For trans-spinal stimulation, MEP thresholds decreased compared to baseline values, and amplitudes, on the contrary, increased, resembling the phenomenon of hypogravitational hyperreflexia. This finding is in line with data observed in other experiments on both male and female participants. MEPs to transcranial stimulation had an opposing dynamic, which may have resulted from the small group size and large inter-subject variability, or from hormonal fluctuations during the menstrual cycle. Central motor conduction time remained unchanged, suggesting that pyramidal tract conductibility was not affected by DI exposure. More research is needed to explore the underlying mechanisms.

show abstract

The Use of “Space” Electrical Myostimulation in Clinical Cardiology on Earth

et al. 2021

View full text Add to dashboard Cite

Comparative Study of the Lower Limb Muscle Tone under the Conditions of Five-day Support Unloading Coupled with Different Regimens of Electromyostimulation

Cited by 3 publications

References 37 publications

The First Female Dry Immersion (NAIAD-2020): Design and Specifics of a 3-Day Study

The First Female Dry Immersion (NAIAD-2020): Design and Specifics of a 3-Day Study

NAIAD-2020: Characteristics of Motor Evoked Potentials After 3-Day Exposure to Dry Immersion in Women

The Use of “Space” Electrical Myostimulation in Clinical Cardiology on Earth

Contact Info

Product

Resources

About