Comparative study of some immunological parameters in case of intestinal parasitic invasion in student

Abstract

A total of 395 practically healthy students were under our supervision. The control group consisted of 22 healthy students matched by age and sex, without concomitant diseases. The students were between the 17-21. It was revealed in 49- giardiasis, in 46- ascariasis, in 26- enterobiosis, in 67-mixed parasitosis. The mixed group is divided into 4 subgroups: a) giardiasis + ascariasis b) giardiasis + enterobiosis c) giardiasis + ascariasis+ enterobiosis d) ascariasis+ enterobiosis. In addition to some immune parameters, the concentration of IgA, IgM, IgG, IgE was determined. The data, which showed the results of the studies, turned out to be lower: in the blood serum of İl-4, almost 4 times(5,6pg/ml) (р <0,05). Based on the data obtained, in can be concluded that intestinal parasitosis is a factor influencing the immune status of patients with parasitism. Intestinal parasitisms, in particular giardiasis, cause intestinal dysbiosis, inhibit the normal intestinal microflora and weaken the local immunity of the digestive tract, as a result of which conditionally pathogenic flora is activated and pathogenic microorganisms develop.