Comparative Study of Phytochemical Constituents and Antimicrobial Activities of Acalypha wilkesiana and Acalypha godseffiana Extracts

Abstract

Aim: The aim of the investigation was to evaluate and compare the phytoconstituents and antimicrobial activities of leaf extracts of two species of Acalypha (A. wilkesiana and A. godseffiana). Methodology: The methods employed include manual pulverization of the air-dried leaves and solvent (ethanol) percolation for 72 hrs. The crude extracts were kept in sterile Mc Cartney bottles and stored in the refrigerator 4±2°C. Thereafter, th ey were screened for phytochemical components. Moreover, they were investigated for antimicrobial activities against Bacillus subtilis, Escherichia coli, Enterococcus faecalis, Klebsiella pneumoniae, Streptococcus pneumoniae, Staphylococcus aureus, Aspergillus flavus, Candida albicans, and Cryptococcus neoformans. Results: From the results obtained during the study, flavonoid, saponin, phobatanin, tannin and alkaloid were found in both A. wilkesiana and A. godseffiana, steroid was found only in Original Research Article

Antioxidant Potentials of Aqueous Leaf Extract of Acalypha godseffiana on Hydrogen Peroxide-Induced Oxidative Stress in Wistar Rats

“…However, experimental groups treated with aqueous extract of A. godseffiana leaf recorded reduced plasma AST and ALT activities when compared with H2O2 alone treated group. This is suggestive that A. godseffiana leaf extract possesses hepatoprotective and antioxidant properties which may be due to the presence of bioactive compounds such as flavonoids, proanthocyanidins, alkaloids, terpenoids, steroids and phenols [18,21,41,42]. This inference is supported by Asekunowo et al [43] who reported a positive relationship between phenolic content and antioxidant activity of extracts of A. godseffiana.…”

CHEMICAL ANALYSIS OF NEW RECORDED SPECIES Acalypha australis L. AT IRAQ

“…Large numbers of herbal plants consider as an important medicinal plants and this importance revels the ability to cure different disease and infections as a result of its content from various secondary metabolites or bioactive compounds (31), and the most important bioactive compounds for Acalypha are flavonoids, phenols, quinones, alkaloids and tannins, which are concentrated in different plants parts from root to flowers and consider as an important character in taxonomical process between different taxa. (38) Acalypha Spp are known as a good resources of an important bioactive compounds with a distinctive roll in the environment and curing disease reveals from several studies in different species all over the world (1,2,11,23,25) while in Iraq there is no study for genus's chemical constitutes. This study was aimed to determine the distinctive features and phytochemical compound in aerial parts of new recorded species Acalypha australis in Iraq.…”