Comparative study of personality traits in patients with bipolar I and II disorder from the five-factor model perspective

Relationship between Chinese adjective descriptors of personality and emotional symptoms in young Chinese patients with bipolar disorders

“…The associations found in patients in the current study confirmed, in part, the hypothesis that traits relating to intelligence are associated with mania in patients with bipolar I disorder, and partly concurred with the findings of the Big-Five personality traits in affective disorders. 19,20,24,31,32 In the current study, the CADP Intelligent trait was significantly correlated with the MDQ in patients with bipolar I disorder, which confirmed the hypothesis that traits relating to intelligence are associated with mania, and concurred with the idea that high intelligence has a greater link to mood disorders. 43 There might also be a Chinese cultural contribution to the relationship between intelligence and bipolar disorders.…”

“…Regarding the disorder subtypes, higher impulsivity, 22 and higher impulsive sensation seeking 23 have been observed in bipolar I compared with bipolar II disorder; and patients with bipolar II disorder have shown higher neuroticism and lower extraversion than patients with bipolar I disorder. 24 To the best of the authors' knowledge, no study has been conducted into whether an emic personality trait in Chinese culture is associated with bipolar disorders. A questionnaire based on the Chinese adjective pool, the Chinese Adjective Descriptors of Personality (CADP), has been developed to measure five dimensions: Intelligent, Emotional, Conscientious, Unsocial and Agreeable; which roughly correspond to the personality domains of the Big-Five Model: Openness to experience, Neuroticism, Conscientiousness, Extraversion and Agreeableness, respectively.…”

“…Chinese people dedicate a large amount of attention and financial resources to a child's education and intelligence assessements, 28,29 and Chinese students sometimes display problems in emotional expression or regulation following an academic failure. 30 Among the Big-Five personality traits in affective disorders, besides the prominent traits of extraversion and neuroticism in bipolar disorders, 19,20,24 higher neuroticism has been noted in patients with unipolar depression. 31,32 The authors hypothesized that (I) traits relating to emotional regulation are associated with depression in patients with bipolar II disorder, and (II) traits relating to intelligence are associated with mania in patients with bipolar I disorder.…”

Bipolar II disorder in patients with a current diagnosis of recurrent depression

“…Many studies have demonstrated that BD‐I and BD‐II are categorically distinct entities differing genetically , biologically , neuropsychologically , and clinically . Moreover, the assumption that BD‐II has a milder course and better outcome than BD‐I has not confirmed. Patients with BD‐II are at higher risk of developing a chronic symptomatic course with predominantly depressive symptoms , and have a poorer overall quality of life even during sustained periods of euthymia .…”

Epistatic Interactions between CREB and CREM Variants in Affective Disorder

“…This issue is particularly concerning if one considers that even among pharmacogenetic studies with a large sample size, results tend to remain conflicting 24. A further concern is related to the use of mood stabilizers with different mechanisms of action that do not allow to reach definitive conclusions with regard to the influence of the SNPs on single mood stabilizers 25. However, our decision to include patients treated with different drugs could have the advantage of being closer to "real world" clinical practice.…”