Comparative Study of Patients in Correct Usage of and Preference for the Swinghaler and Turbuhaler Multidose Inhalers

Chang, Yoon Soo; Park, Myung Jae; Bai, Chunxue; Cai, Baiqiang; Kartasasmita, Cissy B.; Margono, Benjamin P.; Panganiban, Shirley; Yu, Franklin; Wann-Cherng, Perng; Yuan, Hsu Jeng; Wongsa, Adisorn; Ruxrungtham, Kiat; Ahn, Chul Min

doi:10.3109/02770903.2012.688910

Cited by 6 publications

(1 citation statement)

References 19 publications

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“…Jolly et al explained that increase of inhaler usage score is presumably dependent on practical educational training in every step. 19 , 20 Their results showed significant increase in usage scores during three educational intervention sessions. Our experimental group also showed significant improvement in inhaling technique using Turbuhaler system between visits 1 and 3, as measured by inhaler usage score (5.94 and 6.82, respectively; P <0.001).…”

Section: Discussionmentioning

confidence: 95%

Influence of inhaler technique on asthma and COPD control: a multicenter experience

Ilić¹,

Zugic²,

Zvezdin³

et al. 2016

COPD

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BackgroundThe successful management of asthma and chronic obstructive pulmonary disease (COPD) mostly depends on adherence to inhalation drug therapy, the usage of which is commonly associated with many difficulties in real life. Improvement of patients’ adherence to inhalation technique could lead to a better outcome in the treatment of asthma and COPD.ObjectiveThe aim of this study was to assess the utility of inhalation technique in clinical and functional control of asthma and COPD during a 3-month follow-up.MethodsA total of 312 patients with asthma or COPD who used dry powder Turbuhaler were enrolled in this observational study. During three visits (once a month), training in seven-step inhalation technique was given and it was practically demonstrated. Correctness of patients’ usage of inhaler was assessed in three visits by scoring each of the seven steps during administration of inhaler dose. Assessment of disease control was done at each visit and evaluated as: fully controlled, partially controlled, or uncontrolled. Patients’ subjective perception of the simplicity of inhalation technique, disease control, and quality of life were assessed by using specially designed questionnaires.ResultsSignificant improvement in inhalation technique was achieved after the third visit compared to the first one, as measured by the seven-step inhaler usage score (5.94 and 6.82, respectively; P<0.001). Improvement of disease control significantly increased from visit 1 to visit 2 (53.9% and 74.5%, respectively; P<0.001) and from visit 2 to visit 3 (74.5% and 77%, respectively; P<0.001). Patients’ subjective assessment of symptoms and quality of life significantly improved from visit 1 to visit 3 (P<0.001).ConclusionAdherence to inhalation therapy is one of the key factors of successful respiratory disease treatment. Therefore, health care professionals should insist on educational programs aimed at improving patients’ inhalation technique with different devices, resulting in better long-term disease control and improved quality of life.

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Section: Discussionmentioning

confidence: 95%

Influence of inhaler technique on asthma and COPD control: a multicenter experience

Ilić¹,

Zugic²,

Zvezdin³

et al. 2016

COPD

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Dry Powder Inhalation for Pulmonary Delivery: Recent Advances and Continuing Challenges

Carvalho

Watts

Peters

et al. 2015

Pulmonary Drug Delivery

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Technological and practical challenges of dry powder inhalers and formulations

Hoppentocht

Hagedoorn

Frijlink

et al. 2014

Advanced Drug Delivery Reviews

245

126

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In the 50 years following the introduction of the first dry powder inhaler to the market, several developments have occurred. Multiple-unit dose and multi-dose devices have been introduced, but first generation capsule inhalers are still widely used for new formulations. Many new particle engineering techniques have been developed and considerable effort has been put in understanding the mechanisms that control particle interaction and powder dispersion during inhalation. Yet, several misconceptions about optimal inhaler performance manage to survive in modern literature. It is, for example still widely believed that a flow rate independent fine particle fraction contributes to an inhalation performance independent therapy, that dry powder inhalers perform best at 4 kPa (or 60 L/min) and that a high resistance device cannot be operated correctly by patients with reduced lung function. Nevertheless, there seems to be a great future for dry powder inhalation. Many new areas of interest for dry powder inhalation are explored and with the assistance of new techniques like computational fluid dynamics and emerging particle engineering technologies, this is likely to result in a new generation of inhaler devices and formulations, that will enable the introduction of new therapies based on inhaled medicines.

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Comparative Study of Patients in Correct Usage of and Preference for the Swinghaler and Turbuhaler Multidose Inhalers

Abstract: The participants showed no difference in their ability to correctly use a Swinghaler when compared with a Turbuhaler and preferred the Swinghaler. These results suggest that the Swinghaler may be an effective and valuable tool for the management of airway diseases.

Cited by 6 publications

References 19 publications

Influence of inhaler technique on asthma and COPD control: a multicenter experience

Influence of inhaler technique on asthma and COPD control: a multicenter experience

Dry Powder Inhalation for Pulmonary Delivery: Recent Advances and Continuing Challenges

Technological and practical challenges of dry powder inhalers and formulations

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