Comparative Study of Pap Smear Verses Visual Inspection with Acetic Acid in Screening for Cervical Cancer

Abstract

Background: Carcinoma of cervix is 2nd most common cancer globally . India accounts for 4 th global burden . Pap smear is screening method in developed countries .VIA can be an alternative screening method to pap smear in developing countries as it is low cost, simple administration, real time screening of results .Aim of Study : To compare pap smear and VIA in screening for cervical cancer. Objectives of the Study:1. To find out the specificity , sensitivity, PPV , NPV of pap smear for detecting carcinoma of cervix 2. To find out the specificity sensitivity PPV, NPV of VIA detecting carcinoma of cervix.3. To compare the cost effectiveness of performing pap smear and VIA Methodology : Informed oral consent taken .Cervix is to be visualized using a cuscos speculum .Ectocervix and endocervix samples taken and fixed with cytofix and sent for pathologist .TZ is visualized and 3% acetic acid is applied for 1-2 min . If aceto white areas seen it is positive test . colposcopic guides biopsy done for women with any one test positive .Correlation of the above two tests is done by HPE .