lThis research examines the effectiveness of a conceptual framework designed to explain the relationships between several position and setting characteristics (e.g., position level, payment type, union representation, and geographical location of the organization) and employee reactions to the work and the work context. In general, the framework posits that position and setting characteristics influence employee reactions through their impact on the personal attributes of employees and on the characteristics of jobs these employees perform. Results provide substantial support for the conceptual framework. Implications of the findings for future research on the interactions among people, jobs, and organizational conditions are discussed.