Comparative Study of International Prostate Symptom Scores and Urodynamic Parameters in Men and Women with Lower Urinary Tract Symptoms

Abstract

Background: We compared urinary symptoms and urodynamic parameters in men and women with lower urinary tract symptoms. Methods: A total of 164 individuals (76 men and 88 women) were rated according to the International Prostate Symptom Score and underwent a detailed urodynamic investigation. Patients were stratified by age into 2 groups, namely, those <50 years (the younger group) and those >50 years (the elderly group). Results: In the elderly group, scores of voiding symptoms for men were higher than those for women (p = 0.012). Maximum flow rates (Q_max) for women were higher than those for men (p = 0.025 for the younger groups, and p < 0.001 for the elderly groups). Detrusor pressure at Q_max (p < 0.001), opening pressure (p < 0.001) and closing pressure (p = 0.023) were elevated in elderly men vs. in elderly women. A multiple linear regression analysis identified straining (β = 0.479, p < 0.05) and incomplete emptying (β = 0.487, p < 0.05) as the only variables influencing quality of life (QOL) in younger men and women, respectively. In elderly men, nocturia (β = 0.352, p < 0.05) and frequency (β = 0.287, p < 0.05) were significantly associated with QOL. Frequency (β = 0.452, p < 0.05) possibly explained a QOL reduction in elderly women. Conclusions: Our findings suggest that in the elderly patients, storage symptoms are more associated with QOL than voiding symptoms. However, storage symptoms were not associated with QOL in younger men.

Objective Evaluation of Overactive Bladder: Which Surveys Should I Use?

“…The contributing pathophysiologies include a wide differential: storage overactivity, voiding underactivity, outlet obstruction, fluid balance problems, “functional” incontinence of the elderly, and/or sphincter weakness. Conflicting data exists in the literature as to whether symptom questionnaire scores correlate to urodynamic findings such as detrusor overactivity, maximum detrusor pressures, cystometric capacity and stress incontinence [9-12]. …”

Diagnostic value of voiding scores of the “International prostate symptom score” and the “Bristol female lower urinary system symptoms-short form” questionnaires in women with voiding dysfunction

“…On and Ku compared the IPSS and urodynamic parameters and reported that the mean value of IPSS-VS was 10.3 ± 1.0 in women <50 years and 8.6 ± 0.8 in women >50 years. [ 18 ] Carlson et al evaluated women with LUTS with a urodynamic study and reported that high voiding symptoms scores (12.3 points) may increase the suspicion of voiding abnormalities in women with abnormalities on the pressure flow study, although the symptoms were not specific. [ 19 ] In our study, the cutoff value for IPSS-VS was found to be nine.…”