“…Because of its high nutritional quality and biologically active chemicals with good effects on human health, fish is consumed by a wide range of individuals, regardless of their income, age, or health ( Gormley, 2006 ; Lund, 2013 ). The haematological and biochemical profile of fish is a useful tool for determining the well-being position of various aquatic organisms, together with both farmed and wild fish ( Adel et al., 2016 ; da Silva Correa et al., 2017 ; Zhao et al., 2018 ; Sheikh and Ahmed, 2019 ; Fazio, 2019 ; Sidiq and Ahmed, 2020 ; Jan and Ahmed, 2021 ; Jan et al., 2021 ), because these indices provide valuable information for learning about fish reactions to stress, contaminants, hypoxia, nutrition, and habitat, as well as ecological and physiological circumstances ( Cnaani et al., 2004 ; Caruso et al., 2005 ; Walencik and Witeska, 2007 ; Faggio et al., 2014 ; Ahmed and Sheikh, 2019 , 2020 ; Ahmed et al., 2019 ; Fazio, 2019 ; Suljevic and Mitrasinovic-Brulic, 2020 ). Age, diet, sex, fish species and strains, sexual maturity cycle, stocking density and feeding regime, seasonal variations, photoperiod, nutritional state, geographical location, disease, physico-chemical variations, temperature and salinity, sampling conditions, anaesthesia type and laboratory techniques, handling and transport, blood collection, handling, storage time of blood samples, anticoagulants used can strongly influence the results obtained from a haematological and biochemical analysis ( Adeyemo et al., 2009 ; Ferri et al., 2011 ; Gul et al., 2011 ; Jeronimo et al., 2011 ; Witeska and Wargocka, 2011 ; Faggio et al., 2013 ; Fazio et al., 2013 , 2014 ; Witeska et al., 2015 ; Cieplinski et al., 2019 ; Ahmed et al., 2020 ; Jan et al., 2021 ).…”