Comparative study of glassy carbon as an electrode material

Gunasingham, Hari; Fleet, B.

doi:10.1039/an9820700896

Cited by 69 publications

(21 citation statements)

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“…This result is not surprising if we consider that aptamers can be covalently linked directly to the surface of the glassy carbon through their carboxylated groups. 18,19 Selectivity of the sensor was checked against two proteins; bovine serum albumin (BSA) and elastase, using two different experiments. In the first setup, the sensor response to each of the two mentioned proteins was checked separately.…”

Section: Resultsmentioning

confidence: 99%

Solid-contact potentiometric aptasensor based on aptamer functionalized carbon nanotubes for the direct determination of proteins

Düzgün

Maroto

Mairal

et al. 2010

Analyst

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A facile, solid-contact selective potentiometric aptasensor exploiting a network of single-walled carbon nanotubes (SWCNT) acting as a transducing element is described in this work. The molecular properties of the SWCNT surface have been modified by covalently linking aptamers as biorecognition elements to the carboxylic groups of the SWCNT walls. As a model system to demonstrate the generic application of the approach, a 15-mer thrombin aptamer interacts with thrombin and the affinity interaction gives rise to a direct potentiometric signal that can be easily recorded within 15 s. The dynamic linear range, with a sensitivity of 8.0 mV/log a(Thr) corresponds to the 10(-7)-10(-6) M range of thrombin concentrations, with a limit of detection of 80 nM. The aptasensor displays selectivity against elastase and bovine serum albumin and is easily regenerated by immersion in 2 M NaCl. The aptasensor demonstrates the capacity of direct detection of the recognition event avoiding the use of labels, mediators, or the addition of further reagents or analyte accumulation.

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Section: Resultsmentioning

confidence: 99%

Solid-contact potentiometric aptasensor based on aptamer functionalized carbon nanotubes for the direct determination of proteins

Düzgün

Maroto

Mairal

et al. 2010

Analyst

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“…These functionalities have some degrees of acid-base characters [29], which in turn would affect the acid-base characters of the preanodized glassy carbon electrodes. The open-circuit potential of the preanodized electrode would also be sensitive to the changes in pH.…”

Section: Effects Of Phmentioning

confidence: 99%

Preconcentration and Electroanalysis of Copper Species at Electrochemically Activated Glassy Carbon Electrodes

Shiu

Shi

1998

Electroanalysis

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Electrochemically activated glassy carbon electrodes were applied to the preconcentration and electroanalysis of metal species. Activated glassy carbon electrodes were obtained by potentiostatic oxidation at þ2.0 V in 0.5 M sulfuric acid. Copper species were readily extracted onto the modified electrode and were determined electrochemically. Voltammetric peak currents showed linear response for copper concentrations in the range between 1 to 20 mM with a large slope of 2.11 A M ¹1 and a correlation coefficient of 0.997. The reproducibility of the voltammetric measurements was found to be within 7 % RSD for five replicate measurements on copper concentration of 10 mM. The modified electrodes could be applied for repeated copper determinations without appreciable deterioration in electrode response. Results suggest that the preconcentration of copper species onto activated electrodes involved primarily cation-exchange interactions with the surface graphite oxide film.

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“…The ratio of total oxygen to total carbon (obtained from the integral peak intensities normalized using the sensitivity factors [38]) increases from 0.06 for untreated carbon t o (1) 0.11 after pretreatment by a current of 20 mA for 2 seconds and to ( 2 ) The SEM photographs show very little change in the structure of the electrode surface after the galvanostatic pretreatment. It seems that the roughness o f the surface increases only slightly on passage of charges of approximately 20 mC.…”

Section: Properties Of the Electrode Surfacementioning

confidence: 99%

Pretreatment of glassy carbon electrodes by anodic galvanostatic pulses with a large amplitude

et al. 1989

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Glassy carbon electrodes (GCEs) can be activated by the passage of large-amplitude (for example, 20-mA) anodic galvanostatic pulses with durations shorter than 1 second. The increased activity stems from an increase in the rate of charge-transfer reactions and from the adsorption accumulation of the analytes on the electrode surface, which is demonstrated for catecholamines and ascorbic acid. As demonstrated by X-ray photoelectron and fast-atom-bombardment mass spectrometry, the gakanostatic treatment leads to an increase in the amount o f chemisorbed oxygen. Scanning electron microscopy shows very small mechanical changes o f the electrode surface. The activation effect depends on the composition of the test solution and the character of the analytes. There is an optimal electric charge that produces the highest electrode activity and lowers the limits of determination for catecholamines by approximately two orders of magnitude; on further increase in the charge, the electrode activity decreases (due to the formation of a thick layer of graphite oxide). The activation effects are less pronounced in flow-through measurements. The method can be readily implemented for the periodic, automated reactivation of glassy carbon electrodes, but the optimal conditions must be found experimentally for various systems.

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Comparative study of glassy carbon as an electrode material

Cited by 69 publications

References 0 publications

Solid-contact potentiometric aptasensor based on aptamer functionalized carbon nanotubes for the direct determination of proteins

Solid-contact potentiometric aptasensor based on aptamer functionalized carbon nanotubes for the direct determination of proteins

Preconcentration and Electroanalysis of Copper Species at Electrochemically Activated Glassy Carbon Electrodes

Pretreatment of glassy carbon electrodes by anodic galvanostatic pulses with a large amplitude

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