Comparative study of GC‐MS characterization, antioxidant activity and hyaluronidase inhibition of different species of Lavandula and Thymus essential oils

Abstract

The chemical compositions of essential oils of Lavandula angustifolia, Lavandula latifolia, Lavandula hybrida cultivar Grosso and cultivar Super, Thymus zygis with high proportions of thymol and linalool and Thymus hyemalis, from Murcia country (Spain), were studied in relative (%), absolute (mM) and chiral concentrations by GC/MS. Hyaluronidase inhibition and antioxidant activities of the essential oils were evaluated using ABTS•+, DPPH•, ORAC, chelating power, hydroxyl radical, nitric oxide, TBARS and reducing power assays. Linalool and linalyl acetate were the most abundant components in the Lavandula genus whereas thymol, linalool and 1,8‐cineole were the most abundant molecules in the respective Thymus species. Chiral determination of the main components showed (+)‐enantiomers like terpinen‐4‐ol, β‐pinene, borneol and α‐terpineol and (−)‐enantiomers like linalool, linalyl acetate and camphene in Lavandula sp. In the case of Thymus sp. (+)‐enantiomers like α‐pinene, limonene, terpinen‐4‐ol and α‐terpineol and (−)‐enantiomers like borneol were found. Essential oils containing thymol were found especially powerful in all assays but chelating power, ORAC and hydroxyl radical scavenging assays. The capacity for inhibiting hyaluronidase showed that T. zygis with a high proportion of thymol was the most effective inhibitor. Essential oils containing thymol and linalool/linalyl acetate have a potential use as antioxidant agents. Thymol shows strong inhibition of hyaluronidase. Copyright © 2015 John Wiley & Sons, Ltd.

Inhibitory potential of prickly pears and their isolated bioactives against digestive enzymes linked to type 2 diabetes and inflammatory response

“…(a)), respectively. These values are similar to what has been reported for thyme ( Thymus hyemdis ) essential oil . Peel extracts presented the greatest hyaluronidase inhibition when compared to their respective whole fruit and pulp extracts.…”

“…These values are similar to what has been reported for thyme (Thymus hyemdis) essential oil. 35 Peel extracts presented the greatest hyaluronidase inhibition when compared to their respective whole fruit and pulp extracts. Pulp extracts of Sanguinos, Pelota, Vigor, and Diamante also presented high hyaluronidase inhibition of 51.3%, 62.0%, 54.6%, and 50.3%, respectively.…”

Phytochemical profiling of anti‐inflammatory Lavandula extracts via RP–HPLC–DAD–QTOF–MS and –MS/MS: Assessment of their qualitative and quantitative differences

“…Lavandula species are grown for their essential oils (EOs), which are used as aromatic ingredients in perfumes, cosmetics, aromatherapy products, and foods . For these purposes, there are three important species because of their EOs, which contain high amounts of linalool and linalyl acetate, as well as oil yield: true lavender ( L. angustifolia ), spike lavender ( L. latifolia ), and the hybrid lavandin ( L. latifolia × L. angustifolia ) . Other species are also sold as ornamental plants, e.g.…”

The antimicrobial activity of lavender essential oil (Lavandula angustifolia) and its influence on the production performance of broiler chickens

“…Analysis of the LEO chemical composition showed that it was characterised by the highest concentration of compounds of an oxygenated monoterpenes character. It should be emphasised that oxygenated monoterpenes, such as linalool and linalool oxide exhibit antimicrobial and antioxidant activity (Carrasco et al., ; Herman, Tambor, & Herman, ). The composition of essential oil isolated from L. angustifolia Mill., used for medicinal purposes, is specified exactly by the national pharmacopoeia, European Pharmacopoeia.…”

“…Analysis of the LEO chemical composition showed that it was characterised by the highest concentration of compounds of an oxygenated monoterpenes character. It should be emphasised that oxygenated monoterpenes, such as linalool and linalool oxide exhibit antimicrobial and antioxidant activity (Carrasco et al, 2016;Herman, Tambor, & Herman, 2016 properties of LEO (De Rapper et al, 2016;Soković et al, 2010). The diversification of EOs activity may be the result of the varying chemical compositions of varieties of L. angustifolia.…”