Abstract:Children aged 2-12 years scheduled to receive moderately or
highly emetogenic chemotherapy were randomly assigned to arm-A
(fosaprepitant) or arm-B (aprepitant). Children recruited to arm-A
received intravenous ondansetron plus dexamethasone followed by
fosaprepitant infusion. Children recruited to arm-B received the same
drugs as those given to children in arm-A, except that fosaprepitant was
substituted with aprepitant. The primary end point of the study was to
determine the proportion of patients who achiev… Show more
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