Comparative Study of Clinical Factors Predisposing Patients to Proliferative Vitreoretinopathy

Yoshino, Yasumasa; Ideta, Hidenao; Nagasaki, Hiroshi; Uemura, Akinori

doi:10.1097/00006982-198909020-00004

Cited by 57 publications

(35 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…between 1985 and 1989. This high PVR rate may be due to two factors: firstly, the risk of endocular inflammation inherent in cataract extraction and IOL implantation [12][13][14] and, secondly, the fact that many eyes in our series suffered cataract-surgery-related complica tions which, as already shown, are a significant risk factor for PVR.…”

Section: Discussionmentioning

confidence: 77%

Pseudophakic Retinal Detachment

et al. 1991

View full text Add to dashboard Cite

We reviewed 165 cases of non-referred pseudophakic retinal detachment. Fifty-three eyes (32%) had sustained significant complications due to cataract surgery prior to retinal detachment; 45 eyes (27%) presented with grade B, C or D proliferative vitreoretinopathy. The overall reattachment rate was 84%. This was significantly higher in the posterior chamber lens group than in the iris-fixated lens or anterior chamber lens groups (93 vs. 69 and 81%). Our data show that uneventful extracapsular cataract extraction plus posterior chamber lens implantation offers the best chance of successful detachment surgery.

show abstract

Section: Discussionmentioning

confidence: 77%

Pseudophakic Retinal Detachment

et al. 1991

View full text Add to dashboard Cite

show abstract

“…The role of vitreous hemorrhages as predisposing factors for PVR development in human retinal detachment and after retinal surgery has been shown several times (Yoshino et al, 1989;Girard et al, 1994). Moreover, it is well known that blood injection into the vitreal cavity of rabbits induces glial and ®brous membranes (Cleary and Ryan, 1979;Ehrenberg et al, 1984).…”

Section: Discussionmentioning

confidence: 99%

“…Some hemorrhages disappeared before the eighth week. Since the presence of intravitreal blood is a known inducer of PVR, both in human and experimental animals (Cleary and Ryan, 1979;Yoshino et al, 1989;Girard et al, 1994), each treatment group was subdivided into two depending on the absence or presence of hemorrhage during the ®rst and second weeks.…”

Section: Ophthalmoscopic Fundus Inspectionmentioning

confidence: 99%

A Mouse Model of Proliferative Vitreoretinopathy Induced by Dispase

Soler

Gallo

Dodds

et al. 2002

Experimental Eye Research

View full text Add to dashboard Cite

“…9 The pathogenesis of PVR is complex and many studies have investigated the risk factors for its development. [10][11][12][13] We suggest, however, that one of the major principal causes of PVR is failed primary surgery. 14 Retinal reattachment with a single procedure is associated with a better visual outcome and reduced morbidity, 15 and success therefore in primary surgery is of immense importance.…”

Section: Introductionmentioning

confidence: 90%

Prevention and control of proliferative vitreoretinopathy: primary retinal detachment surgery using silicone oil as a planned two-stage procedure in high-risk cases

Alexander¹,

Prasad²,

Ang³

et al. 2007

Eye

View full text Add to dashboard Cite

Aims For rhegmatogenous retinal detachment, reattachment with a single procedure is associated with better visual outcomes. In the past, silicone oil has been used mostly as a last resort following failed primary surgery. This study evaluates a novel approach to patients at high risk of primary failure, using silicone tamponade as the primary stage of a planned two-stage procedure. Methods We report a series of 140 eyes that underwent primary surgery for rhegmatogenous retinal detachment. Patients at higher risk of surgical failure (eg giant retinal tear, inability to posture, poor view, uncertainty of location of primary break, primary proliferative vitreoretinopathy (PVR), multiple tears with rolled posterior edges, retinoschisis/detachment, staphyloma with macular hole) were managed by a planned staged procedure using primary silicone oil tamponade. This was followed by silicone removal at a later date. Results Fifty-four eyes underwent scleral buckling alone, with primary success in 52/54 (96%). Fifty-three eyes underwent vitrectomy and gas, achieving primary success in 50/53 (94%). Thirty-three eyes were classified high risk and managed with primary silicone. Silicone was safely removed in 22/25. In eight eyes, silicone was retained without attempt at removal. In total, primary retinal reattachment was achieved in 128 of 140 eyes (91.4%). Of these, 124 (97%) did not require long-term tamponade. Only four eyes (2.9%) developed PVR. Discussion A planned two-stage approach to highrisk cases of retinal detachment using primary silicone oil tamponade followed by silicone removal can achieve a high primary reattachment rate with less than 3% incidence of PVR.

show abstract

Comparative Study of Clinical Factors Predisposing Patients to Proliferative Vitreoretinopathy

Cited by 57 publications

References 0 publications

Pseudophakic Retinal Detachment

Pseudophakic Retinal Detachment

A Mouse Model of Proliferative Vitreoretinopathy Induced by Dispase

Prevention and control of proliferative vitreoretinopathy: primary retinal detachment surgery using silicone oil as a planned two-stage procedure in high-risk cases

Contact Info

Product

Resources

About