Comparative study of cataract in hypertensive patients and non-hypertensive patients

Mehta, Reshma; Patil, Manjunath; Page, Shubashree

doi:10.5958/2395-1451.2016.00034.2

Cited by 4 publications

(8 citation statements)

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“…Lee et al observed in their study thatconformation structure alteration of protein in lens capsules can be induced by hypertension resulting in aggravating the cataract formation [9] . Mehta et al quoted in their study that Smith PA et al has revealed sympathetic hyperactivity play an integral role in the development of hypertension and its complications [1] . Similar results were found by Masuo K, et al who conducted studies on heightened sympathetic nervous system activity contribute to elevation of blood pressure.…”

Section: Discussionmentioning

confidence: 99%

“…Nearly 12 to 15 million individuals are thought to be blind by cataract worldwide. Cataract occurs a decade earlier in India than the Western world [1] . A recent meta-analysis concluded that the risk of cataract is increased by arterial hypertension, especially the posterior subcapsular subtype [3] .…”

Section: Introductionmentioning

confidence: 94%

“…The prevalence rate is significantly higher in India when compared to Europe (7%) and America (8%). Almost all of the blindness (80%) is preventable [1] . Cataract is opacity in the lens which can block or scatter light.…”

Section: Introductionmentioning

confidence: 99%

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Development of cataract in hypertensive and non-hypertensive patients

Singh¹,

Gupta²

2019

Int. J. Med. Ophthalmol.

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Blindness is a public health problem in developing and developed countries. According to WHO global data for visual impairments 2010, common occurence of blindness was 20.5%.One of the major cause for this is Cataract. Cataract is responsible for about 62.6% of all cases of blindness in India. If cataract left untreated most of the people will in due course become acutely visionless. The motive behind the present study is to find the connection between hypertension and development of cataract. A comparative study was carried for the two months of duration. 200 patients divided in two groups (hypertensive and non-hypertensive) were included in our study. We observed that prevalence of cataract is significantly higher in hypertensive (83.15%) patients as compared to non-hypertensive (70.01%) patients. Hypertension is involved in the pathological pathway of cataract development through an inflammatory mechanism. Nuclear cataract was found to be most common followed by cortical and posterior subcapsular cataract.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 94%

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Development of cataract in hypertensive and non-hypertensive patients

Singh¹,

Gupta²

2019

Int. J. Med. Ophthalmol.

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“…Наш предшествующий анализ в этой популяции показал достижение эффективного контроля АД у каждого 4-го среди гипертоников и у каждого 3-го среди принимающих антигипертензивную терапию [7]. Длительно существующая АГ приводит к утолще- Выявленная связь АГ и катаракты существенно зависела от метаболических факторов, что согласуется с данными других исследований [10]. Например, Lee SM, et al [11] установили, что АГ может вызвать изменение структуры белков капсулы хрусталика, что ухудшает мембранный транспорт и приводит к образованию катаракты.…”

Section: Discussionunclassified

Associations of cardiovascular diseases and type 2 diabetes with ophthalmic diseases in a population sample over 55 years old

Direev

Munts

Mazurenko

et al. 2021

Cardiovasc Ther Prev

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Aim. To study associations of cardiovascular diseases and type 2 diabetes (T2D) with ophthalmic diseases in a population sample of men and women from middle to old age (Novosibirsk).Material and methods. The population cohort was initially studied in 2003-2005 (n=9360, 45-69 years old, Novosibirsk, the Health, Alcohol and Psychosocial factors in Eastern Europe (HAPIEE) project). At the second survey (2015-2017) in a random subsample (n=1011), the following ophthalmic diseases were identified: hypertensive retinopathy (HR), diabetic retinopathy (DR), cataract, glaucoma, age-related macular degeneration (AMD), optic disc abnormalities, etc.Results. The prevalence of HR signs in persons with and without hypertension (HTN) was 81 and 46%, respectively (p<0,001). This association persisted regardless of other factors (odds ratio, 2,27 (95% confidence interval: 1,78-4,17). The prevalence of AMD, cataract and DR increased in HTN, but associations were largely explained by metabolic factors in multivariate models. People with T2D more often than without T2D had signs of DR (9,3 vs 0,4%, p<0,001), AMD (22 vs 17%, p=0,042) and glaucoma (14 vs 7%, p=0,001). Associations of T2D with DR and glaucoma persisted regardless of other factors. Individuals with carotid atherosclerosis (CA) were 1,6 times more likely to have HR than those without CA when adjusted for sex, age, and smoking (p=0,013).Conclusion. In the surveyed population sample of mainly elderly people, a number of associations between cardiometabolic and common ophthalmic diseases were revealed. The identified comorbidities may have important therapeutic and prophylactic applications in an aging population.

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“…Hasil analisis Chi-Square (Continuity Correction) didapatkan bahwa tidak ada hubungan yang segnifikan antara Hipertensi dengan kejadian Katarak pada lansia yang berobat dipoli mata RSUD dr. M. Yunus Bengkulu 2018. Penelitian ini sejalan dengan Mehta, Patil, & Page (2016) bahwa tidak ada hubungan yang signifikan antara katark dengan kejadian hipertensi maupun non hipertensi. Penelitian yang sama dilakukan oleh (Yu et al, 2014) menunjukan bahwa tidak ada hubungan antara hipertensi dengan katark nuclear pada lansia.…”

Section: Penyakitunclassified

Hypertension Relationship with The Incidence of Cataract in The Elderly in The Eye of dr. M. Yunus Bengkulu Hospital

Rahmawati¹,

Juksen²,

Putra³

2018

jkds

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Cataract is eye disease which can cause low vision and blindness. Blindness cases are highest in Indonesia and in the World due to cataract. Cataract could be happened because of degenerative factors that can be influenced by aging. Hypertension is either degenerative disease due to free radicals and decrease in antioxidant so that, can increase of lens opacity.This research aims to know the relationship between hypertension on elderly in Outpatient Eye Care Dr. M Yunus Hospital, Bengkulu Province, years 2018. This technic research used cross sectional. The subject in this research is all of elderly with cataract who getting treatment in Outpatient Eye Care Dr. M. Yunus Bengkulu. The sampling technique uses proportional systematic sampling, obtained 90 respondents. Statistical tests using chi-square (X2). To determine the closeness of the relationship using Contingency Coefficient (C). The result of this research obtained; a) there were 29 respondents (32.2%) with hypertension and 61 respondents or 67.8% without hypertension; b) there were 27 respondents (30.0%) with mature cataract and 63 respondents or 70.0% with immature cataract. The result of Chi Square Analysis obtained p= 0.279 < α = 0.05 meaning there is no relationship between hypertention and cataract

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Comparative study of cataract in hypertensive patients and non-hypertensive patients

Cited by 4 publications

References 0 publications

Development of cataract in hypertensive and non-hypertensive patients

Development of cataract in hypertensive and non-hypertensive patients

Associations of cardiovascular diseases and type 2 diabetes with ophthalmic diseases in a population sample over 55 years old

Hypertension Relationship with The Incidence of Cataract in The Elderly in The Eye of dr. M. Yunus Bengkulu Hospital

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