Comparative study of cardiovascular function and ventricular premature complexes in smokers and nonsmokers during maximal treadmill exercise

McHenry, Paul L.; Faris, James V.; Jordan, John W.; Morris, Stephen N.

doi:10.1016/s0002-9149(77)80156-2

Cited by 30 publications

(10 citation statements)

References 24 publications

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“…3,[21][22][23][24][25][26][27][28][29] In studies that included women, 30,31 the evidence for a protective effect of physical activity was less strong and less consistent than in men. Methodological differences in the measurement of physical activity may explain this variance.…”

Section: Effect In Womenmentioning

confidence: 99%

Prognostic Value of Treadmill Exercise Testing

et al. 1998

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Background-The prognostic value of treadmill exercise testing (TMET) has been studied in selected populations. The generalizability of these data to different populations and to women is uncertain. Methods and Results-A retrospective, population-based cohort study of all persons (1452 men and 741 women) who underwent TMET in years 1987 to 1989 in Olmsted County, Minnesota, was undertaken. Individuals were followed up for all-cause mortality and cardiac events (cardiac deaths, nonfatal myocardial infarction, or congestive heart failure). Sex-specific analyses were performed to determine whether the predictors of outcome and the magnitude of the associations were similar in both sexes. In men, 77 deaths and 106 cardiac events occurred during 8956 person-years of observation; in women, 46 deaths and 54 cardiac events occurred during 4801 person-years of follow-up. Exercise-induced angina, ECG changes, and workload achieved on the TMET were strongly associated with all-cause mortality and cardiac events in both sexes, and the strength of the association was similar. After adjustment, workload was the only TMET variable associated with outcome. A higher workload was associated with a reduction in the risk of cardiac events and of all-cause mortality; the protective effect of exercise capacity was strong and was similar in both sexes. Conclusions-In this population-based cohort, exercise capacity was the TMET variable that exhibited the strongest association with all-cause mortality and cardiac events. This protective effect of exercise capacity was observed in both sexes. (Circulation. 1998;98:2836-2841.)

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Section: Effect In Womenmentioning

confidence: 99%

Prognostic Value of Treadmill Exercise Testing

et al. 1998

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“…It also increased the area and severity of electro cardiographic signs of myocardial ischaemia. The direct haemodynamic effects on the circulation are probably mediated by nicotine which acts on the adrenal medulla (releasing catecholamines) and directly stimulates sym pathetic ganglia (4). The resulting increase in heart rate to blood pressure product increases myocardial oxygen demand and may thus induce isch aemia.…”

Section: Discussionmentioning

confidence: 99%

“…Smoking, however, also has direct effects on the heart which may adversely affect patients with angina [6]. These effects on the blood pressure and heart rate are well known [4], but the influence on resulting myocardial ischaemia in patients with angina is less clear.…”

Section: Introductionmentioning

confidence: 99%

Treatment of Angina Pectoris with Propranolol: the Harmful Effects of Cigarette Smoking

Deanfield¹,

Jonathan²,

Selwyn³

et al. 1981

Cardiology

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The effects of smoking on the treatment of angina has been studied in 10 patients. Each patient underwent 4 randomized 1-week treatments consisting of on and off smoking, and on and off propranolol (360 mg/day). At the end of each treatment a maximal exercise test was performed using 16 praecordial leads. Smoking was associated with a significantly higher heart rate, blood pressure, area and severity of ST-segment depression. This was not abolished by propranolol. Thus, smoking aggrevates the simple haemodynamic variables used to assess myocardial oxygen requirements and the electrocardiographic signs of ischaemia; this is true even after treatment with propranolol.

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“…However, a significant de crease in V 02raax of 27% was recorded among older smokers (40-57 years) compared to nonsmokers of the same age [3,4], The dura tion of maximal exercise was reported to be significantly shorter in smokers and ex-smok ers, than in nonsmokers [5], Moreover, Ste wart et al [6] observed that those who smoked one pack per day had a mean COHb of 5% (range 4-20%). Impairment of physical per formance resulting from elevated COHb is well documented [7][8][9][10][11][12], The main objective of this study was to assess the effect of smok ing on the working capacity of subjects per forming light to moderate work.…”

Section: Introductionmentioning

confidence: 99%

Effect of Cigarette Smoking on Working Capacity

et al. 1992

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Physiological responses to exercise were measured in 39 males (19–45 years old) working as cleaners in the Faculty of Medicine, Kuwait University. There was a graded reduction in maximum oxygen intake (VO_2max) of smokers. This reduction was greatest in those who smoked 20 or more cigarettes per day. A statistically significant decrease (p < 0.05) was recorded in forced expiratory volume (FEV₁) and forced vital capacity (FVC) between smokers and nonsmokers. The results of this study provide quantitative evidence of the adverse effect of smoking on physical working capacity and show the impairment of ventilatory capacity caused by smoking.

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Comparative study of cardiovascular function and ventricular premature complexes in smokers and nonsmokers during maximal treadmill exercise

Cited by 30 publications

References 24 publications

Prognostic Value of Treadmill Exercise Testing

Prognostic Value of Treadmill Exercise Testing

Treatment of Angina Pectoris with Propranolol: the Harmful Effects of Cigarette Smoking

Effect of Cigarette Smoking on Working Capacity

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