Comparative Study of Bupivacaine alone versus Bupivacaine and Dexmedetomidine for Spinal Anesthesia in Hysterectomies

Abstract

[177.74 ± 28.573 min in group I and 353.36 ± 12.138 min in group II (P < 0.001)], total duration of motor block [146.94 ± 9.173 min in group I and 318.36 ± 9.374 min in group II (P < 0.001)], duration of analgesia [283.96 ± 11.165 min in group II and 126.34 ± 7.684 min in group I (P < 0.001)], and total number of doses of rescue analgesia required in 24 h [1.44 ± 0.501 in group II and 2.56 ± 0.675 in group I (P < 0.001)]. Conclusion: Addition of dexmedetomidine to bupivacaine in sub arachnoid block leads to early onset of sensory and motor block with prolonged duration, and patients remained pain free for a longer period with decreased demand for rescue analgesia in the postoperative period as compared with hyperbaric bupivacaine alone without addition of dexmeditomidine.