Comparative study of bipolar eletrocoagulation versus argon plasma coagulation for rectal bleeding due to chronic radiation coloproctopathy

Abstract

BEC and APC are both effective for the therapy of bleeding telangiectasias from CRCP. There are probably no major differences between them. Although APC seemed safer than BEC in this investigation, further studies, involving a much larger population, are needed to assess the complication rates and determine the best management option.

ASGE guideline on the role of endoscopy for bleeding from chronic radiation proctopathy

“…Among the 33 studies, 3 compared APC with other endoscopic modalities or medical therapy. 16,29,46 Specifically, 2 studies compared APC with 4% topical formalin 16,46 and 1 study assessed APC versus bipolar electrocoagulation. 29 A pooled analysis of all 33 studies found an overall clinical success rate of 87% (95% confidence interval, 85%-90%) with an I 2 Z 32 ( Fig.…”

Comparison of Endoscopic Therapies for Chronic Radiation Proctitis: A Systematic Review and Meta-Analysis

“…Response to treatment: Three studies reported response to treatment [40][41][42], shows no difference between therapies. Unfavorable results were found for formalin therapy, as reported by the cohort study Alfadhli [40] (Table 3).…”

“…Adverse effects: Two studies reported adverse effects between endoscopic therapies [40,41], shows differences between the therapies with a lower rate of adverse effects of therapy with APC (Table 3).…”

“…Response to treatment for APC, formalin, and BEC endoscopic therapies: Two studies reported response to treatment [41,42], the heterogeneity test indicated I 2 to be 0%, suggesting homogeneity. Therefore, the fixed-effects model was adopted, and the RD was -0.10 (95% CI: -0.24, 0.05) (Figure 2).…”

“…Chruscielewska-Kiliszek [38] 3 Reject NA Eric Yeoh [42] 3 Acceptable NA Sahakitrungruang C [39] 3 Reject NA Lenz L [41] 3 Acceptable NA Alfadhli A [40] NA Acceptable 8 NA Not Applicable …”