“…Some studies have employed three-dimensional (3D) breast ultrasound image to distinguish between benign and malignant breast masses (9,25,26). In this regard, Chen et al (25) has extracted shape, margin, lesion boundary, echogenicity, posterior acoustic features, and surrounding tissue and was able to classify breast tumors with a sensitivity, specificity, accuracy, PPV, and NPV of 89.6%, 92.8%, 95.9%, 84.5%, and 95.3%, respectively.…”