Comparative Study of Antimicrobial Activity of AgBr and Ag Nanoparticles (NPs)

Abstract

The diverse mechanism of antimicrobial activity of Ag and AgBr nanoparticles against gram-positive and gram-negative bacteria and also against several strains of candida was explored in this study. The AgBr nanoparticles (NPs) were prepared by simple precipitation of silver nitrate by potassium bromide in the presence of stabilizing polymers. The used polymers (PEG, PVP, PVA, and HEC) influence significantly the size of the prepared AgBr NPs dependently on the mode of interaction of polymer with Ag+ ions. Small NPs (diameter of about 60–70 nm) were formed in the presence of the polymer with low interaction as are PEG and HEC, the polymers which interact with Ag+ strongly produce nearly two times bigger NPs (120–130 nm). The prepared AgBr NPs were transformed to Ag NPs by the reduction using NaBH4. The sizes of the produced Ag NPs followed the same trends – the smallest NPs were produced in the presence of PEG and HEC polymers. Prepared AgBr and Ag NPs dispersions were tested for their biological activity. The obtained results of antimicrobial activity of AgBr and Ag NPs are discussed in terms of possible mechanism of the action of these NPs against tested microbial strains. The AgBr NPs are more effective against gram-negative bacteria and tested yeast strains while Ag NPs show the best antibacterial action against gram-positive bacteria strains.

A fast and simple protocol for synthesizing effective antimicrobial silver nanoparticles in non-specialized facilities

“…The antimicrobial activity of our synthesized PVP-AgNPs is comparable to other reported in different studies, using similar culture conditions. MIC values in the literature range from 0.8 µg mL -1 to 13.5 µg mL -1 for S. aureus (Table S1, supplementary material) (13,28), and from 0.4 µg mL -1 to 40 µg mL -1 for C. albicans (Table S2, supplementary material) (29,30). The physicochemical properties of AgNPs depend upon their morphology and capping agent; yet different AgNPs with different traits may display close antimicrobial activity (19).…”

Antibacterial Activity of Biosynthesized Silver Nanoparticles From Viola Serpens Against Multi Drug Resistant Strains of Staphylococcus Aureus and Pseudomonas Aeruginosa

“…[15] Evidently silver nanoparticles exhibited more potency against S. aureus. [16] [17] Moreover, when antibacterial efficacy of AgNPs synthesized from Viola serpens plant extract was compared with the plant extract alone, it clearly shows that the conventional plant extract showing not so much activity as AgNPs does against these MDR bacterial strains, even taken in larger amount approximately 10 times more than AgNPs (Figure 3). From this, it is clearly indicated that these green synthesized AgNPs have shown considerable amount of activity as compared to plant extract.…”

Antimicrobial Nanostructures for Neurodegenerative Infections

“…In addition, they are also shown to produce potent antimicrobial actions by inhibition of microbial growth and reproduction. This property is higher in silver-decorated polymer micelles and polymeric vesicles, antimicrobial polymer micelles and vesicles, and antimicrobial peptide-based vesicles (Suchomel et al, 2015;.…”