Abstract:: The present study sought to compare the effectiveness of a proton pump inhibitor PPI with that of a histamine H 2 receptor antagonist H2RA for treating functional dyspepsia FD in a real-world setting. A multicenter, open-label, randomized trial was conducted. FD patients were randomly assigned to receive either 20 mg, q.d., omeprazole OPZ ; a PPI or 150 mg, b.i.d., ranitidine hydrochloride RAN ; an H2RA for 4 weeks. Any change in the total Gastrointestinal Symptom Rating Scale GSRS score delta at week 4 was … Show more
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