Comparative study between the efficacy of fractional micro-needle radiofrequency and fractional CO2 laser in the treatment of striae distensae

Sobhi, Rehab Mohamed; Mohamed, Iman Shaarawy; Sharkawy, Dina Ahmed El; Wahab, Mona Abd El Fattah Abd El

doi:10.1007/s10103-019-02792-7

Cited by 28 publications

(46 citation statements)

References 12 publications

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“…A slight better efficacy was encountered with FMR, but the difference was not statistically significant ( P = .716). Development of post inflammatory hyperpigmentation was evident with fractional CO 2 in contrast with FMR, and the difference was statistically significant ( P = .001) 21 …”

Section: Discussionmentioning

confidence: 68%

Fractional microneedling radiofrequency in striae alba: Do growth factors add value?

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fawzy

Al‐Rubaiay

et al. 2020

J of Cosmetic Dermatology

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Background Various treatment modalities have been applied to treat striae alba (SA) with low satisfaction rate. Fractional microneedling radiofrequency (FMR) provides deep dermal coagulation, thereby inducing collagen synthesis and tissue tightening. The addition of platelet‐derived lyophilized growth factors may add to the effect of FMR. Objectives To evaluate and compare the efficacy and safety of FMR alone or combined with lyophilized growth factors in the treatment of SA. Methods In this left‐right comparative study, 25 patients suffering from SA on the abdomen received four sessions of FMR with lyophilized growth factors on one side and with saline (as placebo) on the other side at 4 weeks interval. Photographic and biopsy documentation of the progress of the SA was carried out before the start of the treatment and 4 weeks after the last session. Calculation of the width of SA before treatment and after 4 sessions was done by Adobe Photoshop CS6. Results There was a significant improvement in SA width after treatment in both the lyophilized growth factors (P = <.0001) and placebo sides (P = <.0001), the lyophilized growth factors being superior (P = .002). Patient satisfaction was more on the lyophilized growth factors (LGF) side (P = .034). Erythema and hyperpigmentation were less on the lyophilized growth factors side. Histopathologically, both showed improvement with no difference between LGF and placebo (epidermal thickness (P = .456), collagen content (P = .297), elastin content (P = .239)). Conclusion The combination of FMR and lyophilized growth factors improves SA outcome.

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Section: Discussionmentioning

confidence: 68%

Fractional microneedling radiofrequency in striae alba: Do growth factors add value?

Afify

fawzy

Al‐Rubaiay

et al. 2020

J of Cosmetic Dermatology

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“…[16][17][18]24 Recently, NIMRF was also introduced for SD treatments and found to have comparable effects to the fractional CO 2 laser. 13 However, the authors of that report commented that further studies were needed to compare the efficacy of the two approaches for SD treatments with different parameters. 13 In our present study, the parameters we used of the fractional CO 2 laser and NIMRF therapies differed from the literature.…”

Section: Discussionmentioning

confidence: 99%

“…13 However, the authors of that report commented that further studies were needed to compare the efficacy of the two approaches for SD treatments with different parameters. 13 In our present study, the parameters we used of the fractional CO 2 laser and NIMRF therapies differed from the literature. Our current results showed that after three treatments, both procedures effectively improved the atrophic pattern, as revealed by a narrowing in the dermoscopy image and flattening in the VISIA image at follow-up compared with the baseline.…”

Section: Discussionmentioning

confidence: 99%

“…9 Recently, the fractional CO 2 laser has become the most widely used atrophic scar and SD treatment approach. 4,[9][10][11][12][13][14] Fractional photothermolysis can stimulate collagen remodelling, and its efficacy in this regard has been confirmed in several studies. 4 Radiofrequency (RF) devices work by emitting an RF current to the target tissue, which is then converted to heat and causes collagen denaturation and neocollagenesis.…”

Section: Introductionmentioning

confidence: 99%

“…3,16,18,19 However, there are few reports of NIMFR use for abdominal SD treatment. 13 Several studies have compared different modalities for SD treatment efficacy, but most of these investigations have lacked objective evaluation methods. Moreover, the results in most prior studies have indicated a higher patient satisfaction level in free trials but that the level of outcome improvement does not always align with patient satisfaction.…”

Section: Introductionmentioning

confidence: 99%

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Dermoscopy and VISIA imager evaluations of non‐insulated microneedle radiofrequency versus fractional CO₂ laser treatments of striae distensae

Al-Muriesh

Huang

et al. 2020

Acad Dermatol Venereol

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Backgrounds Striae distensae (SD) has a known psychological impact due to the resulting cosmetic disfigurement. Many treatment modalities have been used over the years, but no standard interventions or evaluation methods have been proposed to date. Objective We compared the efficacy and safety of non-insulated microneedle radiofrequency (NIMRF) and fractional CO 2 laser treatments of SD by objective measurements with dermoscopy and VISIA. Methods Fourteen females with severe SD were enrolled. These subjects had been treated three sessions of NIMRF and fractional CO 2 laser for the right and left abdomen, respectively. Dermoscopy and VISIA imaging data, and photographs were collected at baseline and 2 months after the last treatment session. The global aesthetic improvement scale (GIAS) was scored by patients, and blinded investigators, pain score and satisfaction score were also documented. Any side effects were recorded. Results Ten patients completed the study. The GIAS from investigators and patients showed an overall improvement but without a significant difference (P = 0.18, P = 0.17, respectively). The decreased width measured by dermoscopy was between 5% and 32% (right side) and 6-31% (left side). There was no significant difference between both sides in either the per-protocol or intention to treat analyses (P = 0.149, P = 0.161, respectively). The mean pain score was 5.35 and 2.35 on the right side and left side, respectively, which was significant (P = 0.0016). Post-inflammatory hyperpigmentation (PIH) manifested in six patients on their left sides and four patients on their right sides. In most cases, this had resolved by the 3-month follow-up. Conclusion Non-insulated microneedle radiofrequency and fractional CO 2 laser are both effective and safe treatment options for SD. PIH is a possible side effect but is more likely with fractional CO 2 laser treatment. However, it clears up in most cases. Dermoscopy and VISIA are both convenient, digitalized methods of tracking subtle changes and monitoring the efficacy of SD treatments.

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Optical Coherence Tomography‐Assisted Evaluation of Fractional Er:YAG Laser Versus Fractional Microneedling Radiofrequency in Treating Striae Alba

et al. 2020

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Background and Objectives Striae distensae (SD) is a challenging skin condition. Striae alba (SA) represents the chronic late atrophic stage of SD. Fractional laser technology is among the modalities used for treating SD. Lately, fractional microneedling radiofrequency (FMR) is gaining increased popularity in treating SD. The aim of our study was to assess and compare the efficacy of FMR and fractional Er:YAG laser in the treatment of SA. Study Design/Materials and Methods Twenty female patients were enrolled in the study fulfilling all inclusion and exclusion criteria. On a randomly selected half side of the body, the patients were treated with 2940 nm fractional Er:YAG laser while the other half side was treated with the FMR. Results Both modalities showed a significant reduction in the width of the widest striae (P < 0.005); however, there was no significant difference between them. Using optical coherence tomography, all patients demonstrated a mean significant increase in epidermal thickness; however, the FMR‐treated sites showed significantly better results when compared with the ER:YAG‐treated sides (P = 0.029). Scar improvements in both modalities did not correlate to skin type, duration, or site of the striae. Conclusion Er:YAG and FMR represent two safe, effective, tolerable modalities for treating SA and are associated with minimal side effects. Lasers Surg. Med. © 2020 Wiley Periodicals LLC

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Comparative study between the efficacy of fractional micro-needle radiofrequency and fractional CO2 laser in the treatment of striae distensae

Cited by 28 publications

References 12 publications

Fractional microneedling radiofrequency in striae alba: Do growth factors add value?

Fractional microneedling radiofrequency in striae alba: Do growth factors add value?

Dermoscopy and VISIA imager evaluations of non‐insulated microneedle radiofrequency versus fractional CO₂ laser treatments of striae distensae

Optical Coherence Tomography‐Assisted Evaluation of Fractional Er:YAG Laser Versus Fractional Microneedling Radiofrequency in Treating Striae Alba

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Comparative study between the efficacy of fractional micro-needle radiofrequency and fractional CO2 laser in the treatment of striae distensae

Cited by 28 publications

References 12 publications

Fractional microneedling radiofrequency in striae alba: Do growth factors add value?

Fractional microneedling radiofrequency in striae alba: Do growth factors add value?

Dermoscopy and VISIA imager evaluations of non‐insulated microneedle radiofrequency versus fractional CO2 laser treatments of striae distensae

Optical Coherence Tomography‐Assisted Evaluation of Fractional Er:YAG Laser Versus Fractional Microneedling Radiofrequency in Treating Striae Alba

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Dermoscopy and VISIA imager evaluations of non‐insulated microneedle radiofrequency versus fractional CO₂ laser treatments of striae distensae