Comparative Study Between Dexmedetomidine and Clonidine as an Adjunct to Bupivacaine in Brachial Plexus Block in Orthopaedic Surgeries

Abstract

Abstract

Dexmedetomidine versus clonidine as an adjuvant to local anaesthetic in brachial plexus blocks: a meta-analysis of randomised controlled trials

“…1 ). 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 Among 24 included studies, 21 were double-blind and 2 were open-label. One study did not specify the type of blinding.…”

“… Alprazolam 0.25 mg p.o. ND Diclofenec 75 mg im SBO, MBO, SBD, MBD, DA Kakad 24 68/ RCT-Double blind Upper limb orthopedic surgery 0.38% Bupivacaine 40 mL SCBP/ Nerve Stimulator 3-point pin prick scale Modified Bromage Scale ND University of Michigan Sedation Scale (UMSS) ND ND ND SBO, MBO, SBD, MBD, AC Kalyanam 25 60/ RCT-Double blind Forearm and Hand surgery 0.25% Bupivacaine 35 mL SCBP/ Nerve Stimulator 3-point pin prick scale loss of motor function of any nerve ND Modified Ramsay sedation score. (12) ND ND Paracetamol 1 gm iv SBO, MBO, SBD, MBD, DA, SS Kanvee 26 50/ RCT-Double blind Upper limb surgery 0.50% Ropivacaine 30 mL SCBP/ Nerve Stimulator 3-point pin prick scale Modified Bromage Scale VAS ND Midazolam 0.02 mg.kg −1 iv ND Diclofenec 75 mg im SBO, MBO, SBD, MBD, DA Karthik 27 50/ RCT-Double blind Upper limb orthopedic surgery 0.50% Levobupivacaine 30 mL SCBP/ Paresthesia 3-point pin prick scale Modified Bromage Scale VAS ND ND ND ND SBO, MBO, SBD, MBD, DA, SS Kataria 28 60/ RCT-Double blind Upper limb orthopedic surgery 0.50% Levobupivacaine 30 mL SCBP/ Nerve Stimulator 3-point pin prick scale 3-point pin prick scale VAS ND Alprazolam 0.25 mg IV Ketamine-0.5 mg.Kg −1 ND MBD, DA Kirubhar …”