Comparative Studies on the Activity of Glutamic Dehydrogenase and Glutamic-Oxalacetic Transaminase of Rat and Dog Tissues With Special Reference to Thyroid Physiology

Abstract

PATTERN OF ENDOCRINE GLANDS and kidney probably through transamination,not through oxidative deamination. If such is the case,transaminase and glutamic dehydrogenase activities of tissues, which would take part in the metabolism of iodinated compounds including thyroid hormones,will come to be of great significance.

DISTRIBUTION OF ALANINE-α-KETOGLUTARIC AND TYROSINE-α-KETOGLUTARIC TRANSAMINASES AMONG RAT AND PIG TISSUES INCLUDING THYROID, PITUITARY AND ADRENAL

“…In a preceding report, the distribution of glutamic-oxaloacetic(aspartic-a-ketoglutaric) transaminase and glutamic dehydrogenase was investigated with results indicating that these two enzymes were highly active in liver, kidney and heart, and much lower in endocrine tissues especially in the thyroid (Katsura and Yamamoto, 1958). The results were considered of interest with regard to the metabolism of thyroid hormones.…”