2006
DOI: 10.1592/phco.2006.26.1.51
|View full text |Cite
|
Sign up to set email alerts
|

Comparative Safety and Efficacy of Urokinase and Recombinant Tissue Plasminogen Activator for Peripheral Arterial Occlusion: A Meta‐Analysis

Abstract: Urokinase was less effective than rt-PA in successfully lysing acute peripheral arterial occlusion, but it was associated with lower rates of total and minor bleeding. Overall, rt-PA was a reasonable substitute for urokinase, now that urokinase has been removed from the market in the United States. However, judicious monitoring for minor bleeding is necessary.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2006
2006
2011
2011

Publication Types

Select...
4

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(1 citation statement)
references
References 28 publications
0
1
0
Order By: Relevance
“…3,10,15 Yet decompressive surgery results in increased morbidity, risk of spinal instability, postoperative pain, and CSF leakage. 16 Only isolated cases of anaphylaxis or angioedema in patients with thrombosis were observed. Interval laminectomy rarely provides adequate decompression of a solid clot.…”
Section: Discussionmentioning
confidence: 99%
“…3,10,15 Yet decompressive surgery results in increased morbidity, risk of spinal instability, postoperative pain, and CSF leakage. 16 Only isolated cases of anaphylaxis or angioedema in patients with thrombosis were observed. Interval laminectomy rarely provides adequate decompression of a solid clot.…”
Section: Discussionmentioning
confidence: 99%