Comparative Risk of Gout Flares When Initiating or Escalating Various Urate‐Lowering Therapy: A Systematic Review With Network Meta‐Analysis
Dorsa Maher,
Emily Reeve,
Ashley Hopkins
et al.
Abstract:ObjectiveSystematically examine: comparative flare risk post initiation or escalation of different urate‐lowering therapies (ULTs); comparative flare risk with and without concomitant flare prophylaxis; adverse event rates associated with flare prophylaxis; and optimal duration of flare prophylaxis.MethodsWe searched Medline, Embase, Web of Science, Cochrane database and clinical trial registries from inception to November 2021 for trials investigating adults with gout initiating or escalating ULT. We performe… Show more
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