“…There have been several reports of a beneficial effect of transplantation on neuropathy with greater improvement in motor than in sensory function [61,72,80,82,83], Autonomic neuropathy, however, may continue to be troublesome. Furthermore, the pro gression of visual abnormalities may be arrested [1,3,54,71,73,74,77,78,80,83,84], Indeed, in one report from the University of Minnesota, 9 patients (15%) regained functional vision having previously been considered blind [54]. When vision does deteriorate following trans plantation, it is often related to the development of cata racts [75,81], As in those diabetics treated with dialysis, cardiovas cular disease does progress in the posttransplant period [1,2,74], Peripheral vascular disease appears likewise to be unremitting, as evidenced by the fact that between 13 and 50% of these patients have been reported to require amputation of some portion of the extremities [1, 63, 72, 74.…”