Comparative Pore Structure Analysis of Dextran-Coated Polystyrene Particles

Nanoparticles of alkylglyceryl-dextran-graft-poly(lactic acid) for drug delivery to the brain: Preparation and in vitro investigation

“…Various bases (pyridine, DMAP and t-BuOK) were tested: while pyridine's basicity was not sufficient and DMAP yielded only low degrees of substitution (2.1-6.6%), best results (up to 75% degree of substitution) were obtained with t-BuOK at 48 h reaction time and 4 times molar excess of oxirane. Attempts to employ Zn(BF 4 ) 2 as a catalyst in acidic aqueous media (pH 1, as reported in the literature for similar reactions) [29,30] only resulted in products with a low degree of substitution (<1.8%). Following product purification by extraction and dialysis, the modification of dextran with alkyl glyceryl chains was confirmed by FT-IR and 1 H/ 13 C NMR spectroscopy.…”

Adsorption of amphiphilic polysaccharides onto polystyrene latex particles

“…Turbidity measurements [8,19] have shown that PS latex particles flocculate at NaCl concentration of 10 K1 M due to screening of electrostatic repulsions.…”

“…Few systematic studies on adsorption of amphiphilic polysaccharides at the solid-liquid interface are reported in the literature [7,8] contrary to synthetic amphiphilic polymer [9][10][11][12]. Therefore, the aim of this work was to study the adsorption characteristics of a series of model amphiphilic polysaccharides onto latex particles.…”